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Page 1
In vivo imaging of tumors.
Brown E, Munn LL, Fukumura D, Jain RK. Brown E, et al. Cold Spring Harb Protoc. 2010 Jul 1;2010(7):pdb.prot5452. doi: 10.1101/pdb.prot5452. Cold Spring Harb Protoc. 2010. PMID: 20647356 Free PMC article.
Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment.
Askoxylakis V, Ferraro GB, Kodack DP, Badeaux M, Shankaraiah RC, Seano G, Kloepper J, Vardam T, Martin JD, Naxerova K, Bezwada D, Qi X, Selig MK, Brachtel E, Duda DG, Huang P, Fukumura D, Engelman JA, Jain RK. Askoxylakis V, et al. J Natl Cancer Inst. 2015 Nov 7;108(2):djv313. doi: 10.1093/jnci/djv313. Print 2016 Feb. J Natl Cancer Inst. 2015. PMID: 26547932 Free PMC article.
Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma.
Snuderl M, Batista A, Kirkpatrick ND, Ruiz de Almodovar C, Riedemann L, Walsh EC, Anolik R, Huang Y, Martin JD, Kamoun W, Knevels E, Schmidt T, Farrar CT, Vakoc BJ, Mohan N, Chung E, Roberge S, Peterson T, Bais C, Zhelyazkova BH, Yip S, Hasselblatt M, Rossig C, Niemeyer E, Ferrara N, Klagsbrun M, Duda DG, Fukumura D, Xu L, Carmeliet P, Jain RK. Snuderl M, et al. Cell. 2013 Feb 28;152(5):1065-76. doi: 10.1016/j.cell.2013.01.036. Cell. 2013. PMID: 23452854 Free PMC article.
Blockade of MMP14 activity in murine breast carcinomas: implications for macrophages, vessels, and radiotherapy.
Ager EI, Kozin SV, Kirkpatrick ND, Seano G, Kodack DP, Askoxylakis V, Huang Y, Goel S, Snuderl M, Muzikansky A, Finkelstein DM, Dransfield DT, Devy L, Boucher Y, Fukumura D, Jain RK. Ager EI, et al. J Natl Cancer Inst. 2015 Feb 20;107(4):djv017. doi: 10.1093/jnci/djv017. Print 2015 Apr. J Natl Cancer Inst. 2015. PMID: 25710962 Free PMC article.
Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages.
Peterson TE, Kirkpatrick ND, Huang Y, Farrar CT, Marijt KA, Kloepper J, Datta M, Amoozgar Z, Seano G, Jung K, Kamoun WS, Vardam T, Snuderl M, Goveia J, Chatterjee S, Batista A, Muzikansky A, Leow CC, Xu L, Batchelor TT, Duda DG, Fukumura D, Jain RK. Peterson TE, et al. Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4470-5. doi: 10.1073/pnas.1525349113. Epub 2016 Apr 4. Proc Natl Acad Sci U S A. 2016. PMID: 27044097 Free PMC article.
Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2.
Incio J, Ligibel JA, McManus DT, Suboj P, Jung K, Kawaguchi K, Pinter M, Babykutty S, Chin SM, Vardam TD, Huang Y, Rahbari NN, Roberge S, Wang D, Gomes-Santos IL, Puchner SB, Schlett CL, Hoffmman U, Ancukiewicz M, Tolaney SM, Krop IE, Duda DG, Boucher Y, Fukumura D, Jain RK. Incio J, et al. Sci Transl Med. 2018 Mar 14;10(432):eaag0945. doi: 10.1126/scitranslmed.aag0945. Sci Transl Med. 2018. PMID: 29540614 Free PMC article.
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