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A narrow repertoire of transcriptional modules responsive to pyogenic bacteria is impaired in patients carrying loss-of-function mutations in MYD88 or IRAK4.
Alsina L, Israelsson E, Altman MC, Dang KK, Ghandil P, Israel L, von Bernuth H, Baldwin N, Qin H, Jin Z, Banchereau R, Anguiano E, Ionan A, Abel L, Puel A, Picard C, Pascual V, Casanova JL, Chaussabel D. Alsina L, et al. Nat Immunol. 2014 Dec;15(12):1134-42. doi: 10.1038/ni.3028. Epub 2014 Oct 26. Nat Immunol. 2014. PMID: 25344726 Free PMC article.
A transcriptomic reporter assay employing neutrophils to measure immunogenic activity of septic patients' plasma.
Khaenam P, Rinchai D, Altman MC, Chiche L, Buddhisa S, Kewcharoenwong C, Suwannasaen D, Mason M, Whalen E, Presnell S, Susaengrat W, O'Brien K, Nguyen QA, Gersuk V, Linsley PS, Lertmemongkolchai G, Chaussabel D. Khaenam P, et al. J Transl Med. 2014 Mar 11;12:65. doi: 10.1186/1479-5876-12-65. J Transl Med. 2014. PMID: 24612859 Free PMC article.
A genomic approach to human autoimmune diseases.
Pascual V, Chaussabel D, Banchereau J. Pascual V, et al. Annu Rev Immunol. 2010;28:535-71. doi: 10.1146/annurev-immunol-030409-101221. Annu Rev Immunol. 2010. PMID: 20192809 Free PMC article. Review.