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Page 1
Natural products in drug discovery: advances and opportunities.
Atanasov AG, Zotchev SB, Dirsch VM; International Natural Product Sciences Taskforce; Supuran CT. Atanasov AG, et al. Nat Rev Drug Discov. 2021 Mar;20(3):200-216. doi: 10.1038/s41573-020-00114-z. Epub 2021 Jan 28. Nat Rev Drug Discov. 2021. PMID: 33510482 Free PMC article. Review.
Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia.
Membrez M, Migliavacca E, Christen S, Yaku K, Trieu J, Lee AK, Morandini F, Giner MP, Stiner J, Makarov MV, Garratt ES, Vasiloglou MF, Chanvillard L, Dalbram E, Ehrlich AM, Sanchez-Garcia JL, Canto C, Karagounis LG, Treebak JT, Migaud ME, Heshmat R, Razi F, Karnani N, Ostovar A, Farzadfar F, Tay SKH, Sanders MJ, Lillycrop KA, Godfrey KM, Nakagawa T, Moco S, Koopman R, Lynch GS, Sorrentino V, Feige JN. Membrez M, et al. Nat Metab. 2024 Mar;6(3):433-447. doi: 10.1038/s42255-024-00997-x. Epub 2024 Mar 19. Nat Metab. 2024. PMID: 38504132 Free PMC article.
Mitochondrial oxidative capacity and NAD+ biosynthesis are reduced in human sarcopenia across ethnicities.
Migliavacca E, Tay SKH, Patel HP, Sonntag T, Civiletto G, McFarlane C, Forrester T, Barton SJ, Leow MK, Antoun E, Charpagne A, Seng Chong Y, Descombes P, Feng L, Francis-Emmanuel P, Garratt ES, Giner MP, Green CO, Karaz S, Kothandaraman N, Marquis J, Metairon S, Moco S, Nelson G, Ngo S, Pleasants T, Raymond F, Sayer AA, Ming Sim C, Slater-Jefferies J, Syddall HE, Fang Tan P, Titcombe P, Vaz C, Westbury LD, Wong G, Yonghui W, Cooper C, Sheppard A, Godfrey KM, Lillycrop KA, Karnani N, Feige JN. Migliavacca E, et al. Nat Commun. 2019 Dec 20;10(1):5808. doi: 10.1038/s41467-019-13694-1. Nat Commun. 2019. PMID: 31862890 Free PMC article.
Measuring early life adversity: A dimensional approach.
Berman IS, McLaughlin KA, Tottenham N, Godfrey K, Seeman T, Loucks E, Suomi S, Danese A, Sheridan MA. Berman IS, et al. Dev Psychopathol. 2022 May;34(2):499-511. doi: 10.1017/S0954579421001826. Epub 2022 Mar 22. Dev Psychopathol. 2022. PMID: 35314009 Free PMC article. Review.
Maternal weight and gestational diabetes impacts on child health.
Dalrymple KV, El-Heis S, Godfrey KM. Dalrymple KV, et al. Curr Opin Clin Nutr Metab Care. 2022 May 1;25(3):203-208. doi: 10.1097/MCO.0000000000000826. Epub 2022 Feb 23. Curr Opin Clin Nutr Metab Care. 2022. PMID: 35199660 Free PMC article. Review.
A fully convolutional neural network for comprehensive compartmentalization of abdominal adipose tissue compartments in MRI.
Kway YM, Thirumurugan K, Michael N, Tan KH, Godfrey KM, Gluckman P, Chong YS, Venkataraman K, Khoo EYH, Khoo CM, Leow MK, Tai ES, Chan JK, Chan SY, Eriksson JG, Fortier MV, Lee YS, Velan SS, Feng M, Sadananthan SA. Kway YM, et al. Comput Biol Med. 2023 Dec;167:107608. doi: 10.1016/j.compbiomed.2023.107608. Epub 2023 Oct 18. Comput Biol Med. 2023. PMID: 37897959
49 results