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DSS1 restrains BRCA2's engagement with dsDNA for homologous recombination, replication fork protection, and R-loop homeostasis.
Nat Commun. 2024 Aug 17;15(1):7081. doi: 10.1038/s41467-024-51557-6.
Nat Commun. 2024.
PMID: 39152168
Free PMC article.
KDM1A inhibition is effective in reducing stemness and treating triple negative breast cancer.
Zhou M, Venkata PP, Viswanadhapalli S, Palacios B, Alejo S, Chen Y, He Y, Pratap UP, Liu J, Zou Y, Lai Z, Suzuki T, Brenner AJ, Tekmal RR, Vadlamudi RK, Sareddy GR.
Zhou M, et al.
Breast Cancer Res Treat. 2021 Jan;185(2):343-357. doi: 10.1007/s10549-020-05963-1. Epub 2020 Oct 14.
Breast Cancer Res Treat. 2021.
PMID: 33057995
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