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Page 1
Intensive Diabetes Treatment and Cardiovascular Outcomes in Type 1 Diabetes: The DCCT/EDIC Study 30-Year Follow-up.
Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Group. Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Group. Diabetes Care. 2016 May;39(5):686-93. doi: 10.2337/dc15-1990. Epub 2016 Feb 9. Diabetes Care. 2016. PMID: 26861924 Free PMC article. Clinical Trial.
We now assess whether intensive therapy compared with conventional therapy during the Diabetes Control and Complications Trial (DCCT) affected the incidence of cardiovascular disease over 30 years of follow-up. RESEARCH DESIGN AND METHODS
We now assess whether intensive therapy compared with conventional therapy during the Diabetes Control and Complications
Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes.
Nathan DM, Cleary PA, Backlund JY, Genuth SM, Lachin JM, Orchard TJ, Raskin P, Zinman B; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study Research Group. Nathan DM, et al. N Engl J Med. 2005 Dec 22;353(25):2643-53. doi: 10.1056/NEJMoa052187. N Engl J Med. 2005. PMID: 16371630 Free PMC article. Clinical Trial.
We studied whether the use of intensive therapy as compared with conventional therapy during the Diabetes Control and Complications Trial (DCCT) affected the long-term incidence of cardiovascular disease. METHODS: The DCCT randomly …
We studied whether the use of intensive therapy as compared with conventional therapy during the Diabetes Control and Compl
A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.
van Zuydam NR, Ahlqvist E, Sandholm N, Deshmukh H, Rayner NW, Abdalla M, Ladenvall C, Ziemek D, Fauman E, Robertson NR, McKeigue PM, Valo E, Forsblom C, Harjutsalo V; Finnish Diabetic Nephropathy Study (FinnDiane); Perna A, Rurali E, Marcovecchio ML, Igo RP Jr, Salem RM, Perico N, Lajer M, Käräjämäki A, Imamura M, Kubo M, Takahashi A, Sim X, Liu J, van Dam RM, Jiang G, Tam CHT, Luk AOY, Lee HM, Lim CKP, Szeto CC, So WY, Chan JCN; Hong Kong Diabetes Registry Theme-based Research Scheme Project Group; Ang SF, Dorajoo R, Wang L, Clara TSH, McKnight AJ, Duffy S; Warren 3 and Genetics of Kidneys in Diabetes (GoKinD) Study Group; Pezzolesi MG; GENIE (GEnetics of Nephropathy an International Effort) Consortium; Marre M, Gyorgy B, Hadjadj S, Hiraki LT; Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group; Ahluwalia TS, Almgren P, Schulz CA, Orho-Melander M, Linneberg A, Christensen C, Witte DR, Grarup N, Brandslund I, Melander O, Paterson AD, Tregouet D, Maxwell AP, Lim SC, Ma RCW, Tai ES, Maeda S, Lyssenko V, Tuomi T, Krolewski AS, Rich SS, Hirschhorn JN, Florez JC, Dunger D, Pedersen O, Hansen T, Rossing P, Remuzz… See abstract for full author list ➔ van Zuydam NR, et al. Diabetes. 2018 Jul;67(7):1414-1427. doi: 10.2337/db17-0914. Epub 2018 Apr 27. Diabetes. 2018. PMID: 29703844 Free PMC article.
Identification of sequence variants robustly associated with predisposition to diabetic kidney disease (DKD) has the potential to provide insights into the pathophysiological mechanisms responsible. We conducted a genome-wide association study (GWAS) of DKD in type 2 di
Identification of sequence variants robustly associated with predisposition to diabetic kidney disease (DKD) has the potential to pro …
Burden of Urological Complications in Men and Women With Long-standing Type 1 Diabetes in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Cohort.
Wessells H, Braffett BH, Holt SK, Jacobson AM, Kusek JW, Cowie C, Dunn RL, Sarma AV; DCCT/EDIC Study Group. Wessells H, et al. Diabetes Care. 2018 Oct;41(10):2170-2177. doi: 10.2337/dc18-0255. Epub 2018 Aug 13. Diabetes Care. 2018. PMID: 30104298 Free PMC article.
We sought to determine prevalence of urological complications in persons with type 1 diabetes, associations with clinical and diabetes-related factors, and rates of emergence, persistence, and remission. RESEARCH DESIGN AND METHODS: This ancilla …
We sought to determine prevalence of urological complications in persons with type 1 diabetes, associations with clinical
Mortality in Type 1 Diabetes in the DCCT/EDIC Versus the General Population.
Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Group. Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Group. Diabetes Care. 2016 Aug;39(8):1378-83. doi: 10.2337/dc15-2399. Epub 2016 Jul 13. Diabetes Care. 2016. PMID: 27411699 Free PMC article.
OBJECTIVE: Historically, mortality in type 1 diabetes has exceeded that in the general population. We compared mortality in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complicat
OBJECTIVE: Historically, mortality in type 1 diabetes has exceeded that in the general population. We compared mortality in the Di
Development and progression of renal insufficiency with and without albuminuria in adults with type 1 diabetes in the diabetes control and complications trial and the epidemiology of diabetes interventions and complications study.
Molitch ME, Steffes M, Sun W, Rutledge B, Cleary P, de Boer IH, Zinman B, Lachin J; Epidemiology of Diabetes Interventions and Complications Study Group. Molitch ME, et al. Diabetes Care. 2010 Jul;33(7):1536-43. doi: 10.2337/dc09-1098. Epub 2010 Apr 22. Diabetes Care. 2010. PMID: 20413518 Free PMC article.
OBJECTIVE: This multicenter study examined the impact of albumin excretion rate (AER) on the course of estimated glomerular filtration rate (eGFR) and the incidence of sustained eGFR <60 ml/min/1.73 m(2) in type 1 diabetes up to year 14 of the Epidemiology of …
OBJECTIVE: This multicenter study examined the impact of albumin excretion rate (AER) on the course of estimated glomerular filtration rate …
DNA methylation mediates development of HbA1c-associated complications in type 1 diabetes.
Chen Z, Miao F, Braffett BH, Lachin JM, Zhang L, Wu X, Roshandel D, Carless M, Li XA, Tompkins JD, Kaddis JS, Riggs AD, Paterson AD; DCCT/EDIC Study Group; Natarajan R. Chen Z, et al. Nat Metab. 2020 Aug;2(8):744-762. doi: 10.1038/s42255-020-0231-8. Epub 2020 Jul 20. Nat Metab. 2020. PMID: 32694834 Free PMC article.
Metabolic memory, the persistent benefits of early glycaemic control on preventing and/or delaying the development of diabetic complications, has been observed in the Diabetes Control and Complications Trial (DCCT) and in th …
Metabolic memory, the persistent benefits of early glycaemic control on preventing and/or delaying the development of diabetic
Long-term renal outcomes of patients with type 1 diabetes mellitus and microalbuminuria: an analysis of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications cohort.
de Boer IH, Rue TC, Cleary PA, Lachin JM, Molitch ME, Steffes MW, Sun W, Zinman B, Brunzell JD; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study Research Group; White NH, Danis RP, Davis MD, Hainsworth D, Hubbard LD, Nathan DM. de Boer IH, et al. Arch Intern Med. 2011 Mar 14;171(5):412-20. doi: 10.1001/archinternmed.2011.16. Arch Intern Med. 2011. PMID: 21403038 Free PMC article. Clinical Trial.
BACKGROUND: Microalbuminuria is a common diagnosis in the clinical care of patients with type 1 diabetes mellitus. Long-term outcomes after the development of microalbuminuria are variable. METHODS: We quantified the incidence of and risk factors for l …
BACKGROUND: Microalbuminuria is a common diagnosis in the clinical care of patients with type 1 diabetes mellitus. Long …
Comparison of digital and film grading of diabetic retinopathy severity in the diabetes control and complications trial/epidemiology of diabetes interventions and complications study.
Hubbard LD, Sun W, Cleary PA, Danis RP, Hainsworth DP, Peng Q, Susman RA, Aiello LP, Davis MD; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study Research Group. Hubbard LD, et al. Arch Ophthalmol. 2011 Jun;129(6):718-26. doi: 10.1001/archophthalmol.2011.136. Arch Ophthalmol. 2011. PMID: 21670338 Clinical Trial.
OBJECTIVE: To compare diabetic retinopathy (DR) severity as evaluated by digital and film images in a long-term multicenter study, as the obsolescence of film forced the Diabetes Control and Complications Trial/Epidemiology of Diabetes
OBJECTIVE: To compare diabetic retinopathy (DR) severity as evaluated by digital and film images in a long-term multicenter study, as …
Comparison of fingerstick hemoglobin A1c levels assayed by DCA 2000 with the DCCT/EDIC central laboratory assay: results of a Diabetes Research in Children Network (DirecNet) Study.
Tamborlane WV, Kollman C, Steffes MW, Ruedy KJ, Dongyuan X, Beck RW, Chase P, Fox LA, Wilson DM, Tsalikian E; Diabetes Research in Children Network (DirecNet) Study Group. Tamborlane WV, et al. Pediatr Diabetes. 2005 Mar;6(1):13-6. doi: 10.1111/j.1399-543X.2005.00088.x. Pediatr Diabetes. 2005. PMID: 15787896
BACKGROUND: The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) high-performance liquid chromatography (HPLC) method for measuring hemoglobin A1c (H …
BACKGROUND: The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions
25 results