User profiles for Brian Chen

Brian H. Chen

- Verified email at ucsf.edu - Cited by 11041

Brian Chen

- Verified email at ccny.cuny.edu - Cited by 1939

Brian (Po-Han) Chen

- Verified email at jefferson.edu - Cited by 1598

Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex

JT Trachtenberg, BE Chen, GW Knott, G Feng… - Nature, 2002 - nature.com
Do new synapses form in the adult cortex to support experience-dependent plasticity? To
address this question, we repeatedly imaged individual pyramidal neurons in the mouse barrel …

Quantization index modulation: A class of provably good methods for digital watermarking and information embedding

B Chen, GW Wornell - IEEE Transactions on Information theory, 2001 - ieeexplore.ieee.org
We consider the problem of embedding one signal (eg, a digital watermark), within another "host"
signal to form a third, "composite" signal. The embedding is designed to achieve …

Deep eutectic solvents: A review of fundamentals and applications

BB Hansen, S Spittle, B Chen, D Poe, Y Zhang… - Chemical …, 2020 - ACS Publications
Deep eutectic solvents (DESs) are an emerging class of mixtures characterized by significant
depressions in melting points compared to those of the neat constituent components. …

[HTML][HTML] DNA methylation-based measures of biological age: meta-analysis predicting time to death

BH Chen, RE Marioni, E Colicino, MJ Peters… - Aging (Albany …, 2016 - ncbi.nlm.nih.gov
Estimates of biological age based on DNA methylation patterns, often referred to as “epigenetic
age”,“DNAm age”, have been shown to be robust biomarkers of age in humans. We …

[HTML][HTML] An epigenetic biomarker of aging for lifespan and healthspan

ME Levine, AT Lu, A Quach, BH Chen… - Aging (albany …, 2018 - ncbi.nlm.nih.gov
Identifying reliable biomarkers of aging is a major goal in geroscience. While the first
generation of epigenetic biomarkers of aging were developed using chronological age as a …

Experience-dependent plasticity of dendritic spines in the developing rat barrel cortex in vivo

B Lendvai, EA Stern, B Chen, K Svoboda - Nature, 2000 - nature.com
Do changes in neuronal structure underlie cortical plasticity 1 , 2 ? Here we used time-lapse
two-photon microscopy 3 , 4 of pyramidal neurons in layer 2/3 of developing rat barrel cortex …

DNA methylation age of blood predicts all-cause mortality in later life

RE Marioni, S Shah, AF McRae, BH Chen, E Colicino… - Genome biology, 2015 - Springer
Background DNA methylation levels change with age. Recent studies have identified
biomarkers of chronological age based on DNA methylation levels. It is not yet known whether …

[HTML][HTML] The molecular diversity of Dscam is functionally required for neuronal wiring specificity in Drosophila

BE Chen, M Kondo, A Garnier, FL Watson… - Cell, 2006 - cell.com
Alternative splicing of Dscam generates an enormous molecular diversity with maximally
38,016 different receptors. Whether this large diversity is required in vivo is currently unclear. …

Prolonged operative duration increases risk of surgical site infections: a systematic review

H Cheng, BPH Chen, IM Soleas, NC Ferko… - Surgical …, 2017 - liebertpub.com
Background: The incidence of surgical site infection (SSI) across surgical procedures,
specialties, and conditions is reported to vary from 0.1% to 50%. Operative duration is often cited …

[HTML][HTML] Epigenetic clock analysis of diet, exercise, education, and lifestyle factors

A Quach, ME Levine, T Tanaka, AT Lu, BH Chen… - Aging (albany …, 2017 - ncbi.nlm.nih.gov
Behavioral and lifestyle factors have been shown to relate to a number of health-related
outcomes, yet there is a need for studies that examine their relationship to molecular aging rates…