| | DL | Signed (The New England Patriots signed DL Mike Purcell.) |
| | RB | Activated (The New England Patriots activated RB Antonio Gibson from the Non-football injury list.) |
| | DT | Signed (The New England Patriots signed DT Josiah Bronson.) |
| | RB | Activated (The New England Patriots activated RB Terrell Jennings.) |
| | CB | Released (The New England Patriots released CB Kaleb Ford-Dement.) |
| | C | Placed on PUPL (The New England Patriots placed C Jake Andrews on PUP list.) |
| | WR | Placed on PUPL (The New England Patriots placed WR Kendrick Bourne on PUP list.) |
| | OG | Placed on PUPL (The New England Patriots placed OG Cole Strange on PUP list.) |
| | LB | Placed on PUPL (The New England Patriots placed LB Sione Takitaki on PUP list.) |
| | RB | Reserve/non football injury (The New England Patriots placed RB Antonio Gibson on NON list.) |
| | LB | Released (The New England Patriots released LB Jontrey Hunter.) |
| | RB | Placed on PUPL (The New England Patriots placed RB Terrell Jennings on the PUP list.) |
| | LB | Reserve/non football injury (The New England Patriots placed LB Jontrey Hunter on the Non-football injury lists.) |
| | WR | Declared Free Agent (WR Tre Nixon declared free agency.) |
| | DB | Released (The New England Patriots released DB John Pupel.) |
| | WR | Released (The New England Patriots released Beau Corrales.) |
| | K | Released (The New England Patriots released K Vincent Blanchard.) |
| | CB | Released (The New England Patriots released CB Trajan Bandy.) |
| | OT | Released (The New England Patriots released OT Tariq Stewart.) |
| | OG | Released (The New England Patriots released OG Ryan Johnson.) |
| | OG | Signed (The New England Patriots signed OL Liam Fornadel.) |
| | WR | Signed (The New England Patriots signed WR Ja'Lynn Polk.) |
| | LB | Released (The New England Patriots released LB Jay Person.) |
| | LB | Claimed (The New England Patriots claimed LB Steele Chambers off waivers.) From |
| | WR | Signed (The New England Patriots signed WR Ja'Lynn Polk.) |
| | WR | Signed (The New England Patriots signed WR JaQuae Jackson.) |
| | WR | Released (The New England Patriots released WR T.J. Luther.) |
| | G | Signed (The New England Patriots signed G Layden Robinson.) |
| | OL | Waived (The New England Patriots waived OT Andrew Stueber.) |
| | WR | Signed (The New England Patriots signed WR David Wallis.) |
| | T | Signed (The New England Patriots signed T Caedan Wallace.) |
| | QB | Signed (The New England Patriots signed QB Drake Maye.) |
| | QB | Signed (The New England Patriots signed QB Drake Maye.) |
| | WR | Signed (The New England Patriots signed WR Javon Baker.) |
| | DE | Signed (The New England Patriots signed LB Jotham Russell.) |
| | RB | Signed (The New England Patriots signed RB Terrell Jennings.) |
| | OG | Signed (The New England Patriots signed OL Ryan Johnson.) |
| | RB | Released (The New England Patriots released RB Ke'Shawn Vaughn.) |
| | TE | Signed (The New England Patriots signed TE Jaheim Bell.) |
| | QB | Signed (The New England Patriots signed QB Joe Milton.) |
| | DB | Signed (The New England Patriots signed DB Marcellas Dial.) |
| | K | Signed (The New England Patriots signed K Vincent Blanchard.) |
| | CB | Signed (The New England Patriots signed CB Trajan Bandy.) |
| | OT | Signed (The New England Patriots signed OT Tairiq Stewart.) |
| | WR | Signed (The New England Patriots signed WR Beau Corrales.) |
| | LB | Signed (The New England Patriots signed DE Jay Person.) |
| | DB | Signed (The New England Patriots signed DB John Pupel.) |
| | QB | Released (The New England Patriots released QB Nathan Rourke.) |
| | K | Signed (The New England Patriots signed K Joey Slye.) |
| | TE | Signed (The New England Patriots signed TE Jacob Warren.) |
| | S | Signed (The New England Patriots signed S Dell Pettus.) |
| | RB | Signed (The New England Patriots signed RB Deshaun Fenwick.) |
| | RB | Signed (The Dallas Cowboys have signed RB Ezekiel Elliot.) To |
| | OT | Signed (The New England Patriots signed OT Zuri Henry.) |
| | CB | Signed (The New England Patriots signed CB Kaleb Ford-Dement.) |
| | C | Signed (The New England Patriots signed C Charles Turner.) |
| | OLB | Signed (The New England Patriots signed OLB Oshane Ximines.) |
| | TE | Signed (The New England Patriots signed TE Mitchell Wilcox.) |
| | DB | Retired (DB Cody Davis retired from the NFL.) |
| | CB | Declared Free Agent (DB Myles Bryant elected free agency.) |
| | S | Signed (The New England Patriots signed SAF Jaylinn Hawkins.) |
| | OT | Declared Free Agent (OL Trent Brown elected free agency.) |
| | WR | Signed (The New England Patriots signed WR K.J. Osborn.) |
| | TE | Signed (The New England Patriots signed TE Austin Hooper.) |
| | DT | Signed (The New England Patriots signed DT Armon Watts.) |
| | TE | Declared Free Agent (TE Pharaoh Brown elected free agency.) |
| | G | Signed (The New England Patriots signed G Nick Leverett.) |
| | DB | Declared Free Agent (DB Jalen Mills elected free agency.) |
| | LB | Signed (The New England Patriots signed LB Sione Takitaki.) |
| | TE | Declared Free Agent (TE Mike Gesicki elected free agency.) |
| | QB | Signed (The New England Patriots signed QB Jacoby Brissett.) |
| | LB | Released (The New England Patriots released LB Chris Board.) |
| | RB | Signed (The New England Patriots signed RB Antonio Gibson.) |
| | LB | Declared Free Agent (LB Mack Wilson elected free agency.) |
| | WR | Released (The New England Patriots released WR DeVante Parker.) |
| | QB | Traded (The New England Patriots traded QB Mac Jones to the Jacksonville Jaguars.) To |
| | OT | Signed (The New England Patriots signed T Chukwuma Okafor.) |
| | CB | Released (The New England Patriots released CB J.C. Jackson.) |
| | WR | Retired (WR Matthew Slater retired from the NFL.) |
| | DL | Released (The New England Patriots released DL Lawrence Guy.) |
| | OL | Retired (OL James Ferentz retired from the NFL.) |
| | DB | Released (The New England Patriots released SAF Adrian Phillips.) |
| | WR | Signed (The New England Patriots singed WR Kawaan Baker to a reserve/future contract.) |
| | G | Signed (The New England Patriots signed G Michael Jordan to a reserve/future contract.) |
| | OL | Pract. squad add (The New England Patriots assigned OL Andrew Stueber to the practice squad.) |
| | TE | Pract. squad add (The New England Patriots assigned TE Matt Sokol to the practice squad.) |
| | TE | Signed (The New England Patriots signed TE La'Michael Pettway from the practice squad.) |