“Vítor is an excepcional biomedical researcher, a detail oriented scientist with a broad perspective of the biopharmaceutical industry. A team player with excellent project management capabilities and great interpersonal skills.”
Vítor Espírito Santo
London, England, United Kingdom
2K followers
500+ connections
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With a PhD in Stem Cells, Regenerative Medicine & Tissue Engineering and 15 years of…
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After an amazing five-year journey in San Francisco, I’m filled with gratitude and joy to announce that I’m back in Portugal. I am immensely…
After an amazing five-year journey in San Francisco, I’m filled with gratitude and joy to announce that I’m back in Portugal. I am immensely…
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Join the cell-cultured meat, poultry, and seafood industry in the San Francisco Bay Area next month at the 7th edition of the Cultured Meat…
Join the cell-cultured meat, poultry, and seafood industry in the San Francisco Bay Area next month at the 7th edition of the Cultured Meat…
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How do you achieve a scalable, cost-effective #bioprocess? Hoxton Farms is combining cell biology and mathematical modeling, as they develop…
How do you achieve a scalable, cost-effective #bioprocess? Hoxton Farms is combining cell biology and mathematical modeling, as they develop…
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Universidade do Minho
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Activities and Societies: - Co-founder and Head of Pedagogical Department of "Gabinete de alunos de Engenharia Biomedica" (GAEB) at University of Minho. - Responsible for negotiations between students and department leaders during implementation of Bologna Process. - Activation of ERASMUS program for Biomedical Engineering students. Part of the first group (of 3) students that embarked for international exchange program in 2006. - Member of CAUM, the university Choir, for approximately 3 years.
- First class of students of Biomedical Engineering at University of Minho, Portugal.
- Major in Biomaterials, Rehabilitation and Biomechanics.
Publications
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Layer-by-Layer Assembled Cell Instructive Nanocoatings containing Platelet Lysate
Biomaterials
Great efforts have been made to introduce growth factors (GFs) onto 2D/3D constructs in
order to control cell behavior. Platelet Lysate (PL) presents itself as a cost-effective source of multiple
GFs and other proteins. The instruction given by a construct-PL combination will depend on how its
instructive cues are presented to the cells. The content, stability and conformation of the GFs affect
their instruction. Strategies for a controlled incorporation of PL are needed. Herein, PL…Great efforts have been made to introduce growth factors (GFs) onto 2D/3D constructs in
order to control cell behavior. Platelet Lysate (PL) presents itself as a cost-effective source of multiple
GFs and other proteins. The instruction given by a construct-PL combination will depend on how its
instructive cues are presented to the cells. The content, stability and conformation of the GFs affect
their instruction. Strategies for a controlled incorporation of PL are needed. Herein, PL was
incorporated into nanocoatings by layer-by-layer assembling with polysaccharides presenting
different sulfation degrees (SD) and charges. Heparin and several marine polysaccharides were tested
to evaluate their PL and GF incorporation capability. The consequent effects of those multilayers on
human adipose derived stem cells (hASCs) were assessed in short-term cultures. Both nature of the
polysaccharide and SD were important properties that influenced the adsorption of PL, vascular
endothelial growth factor (VEGF), fibroblast growth factor b (FGFb) and platelet derived growth factor
(PDGF). The sulfated polysaccharides-PL multilayers showed to be efficient in the promotion of
morphological changes, serum-free adhesion and proliferation of high passage hASCs (P>5). These
biomimetic multilayers promise to be versatile platforms to fabricate instructive devices allowing a
tunable incorporation of PL.Other authorsSee publication
Languages
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Englisch
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Spanish
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Portuguese
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Burritos across the nation! Our new JUST Egg Breakfast Burritos are now rolling out to all Whole Foods Market locations across the U.S. Find them in…
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In the #LifeAtHoxtonFarms, we know that starting a new job can feel like a big bite to chew. That’s why we have a buddy system to help new team…
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Nutreco completed construction and started commercial operations of the world's first #cell #feed #production #facility in #Boxmeer, #TheNetherlands.…
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Excited to see our CEO Maria Cho recognized by Forbes. Congratulations to all 6 of these truly remarkable, change-making leaders!
Excited to see our CEO Maria Cho recognized by Forbes. Congratulations to all 6 of these truly remarkable, change-making leaders!
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I am deeply grateful for this moment. After five years of the inauguration of the #alternativeprotein program at Nutreco , we are celebrating a…
I am deeply grateful for this moment. After five years of the inauguration of the #alternativeprotein program at Nutreco , we are celebrating a…
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The incredible judges and staff of the XPRIZE Feed the Next Billion team here in Abu Dhabi for the next round of judging srructured chicken breast or…
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