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The Royals and Cardinals will play two on Wednesday after their Tuesday game was postponed due to weather. Game 1 comes at 1:45 p.m. ET in St. Louis. Kansas City is third in the AL Central with a 49-43 mark, but it is trying to regain some momentum after losing three of its last four, including two of three at Colorado. The Cardinals are second in the AL central at 48-42. With both teams battling for wild-card positioning in their respective leagues, Wednesday's interleague twin bill looms large. The projected starters for Game 1 are Alec Marsh (6-6, 4.57 ERA) for K.C. and Andre Pallante (4-3, 4.00 ERA) for St. Louis. 

The latest Cardinals vs. Royals odds via SportsLine consensus list St. Louis as the -131 favorite (risk $131 to win $100) on the money line. The over/under is 8.5. Before making any Royals vs. Cardinals picks, be sure to check out the MLB predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It entered Week 16 of the 2024 MLB season a profitable 49-37 on all-top rated MLB picks this season. Dating back to last season, it is on a 24-9 roll on top-rated run-line picks (+1077). Anybody following has seen strong returns. 

Now, the model has set its sights on Royals vs. Cardinals and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Now, here are several MLB odds and betting lines for Cardinals vs. Royals:

  • Cardinals vs. Royals money line: Cardinals -131, Royals +111
  • Cardinals vs. Royals run line: Cardinals -1.5 (+156) 
  • Cardinals vs. Royals over/under: 8.5 runs
  • Cardinals vs. Royals picks: See picks at SportsLine

Top Cardinals vs. Royals pick

For Royals vs. Cardinals, one of the top picks from SportsLine's model is that Royals shortstop Bobby Witt goes Over 1.5 total bases (-128). The model is projecting 2.3 total bases for the young star. 

The 24-year-old righty is absolutely mashing this season. He has a .324 batting average with a .564 slugging percentage and an OPS of .936. His 25 doubles, nine triples and 15 home runs are all pacing to be career highs. Those are all notable marks in this situation since one extra-base hit would make this prop hit. 

And though Witt hits both lefties and righties well, his power numbers are slightly better against righties, which is what he's scheduled to see in Pallante in Game 1 on Wednesday. See more picks at SportsLine.

How to make Cardinals vs. Royals picks

In addition to that prop pick, the model also says one side of the money line has all the value. You can only get the MLB model's picks and analysis at SportsLine.

So who wins Royals vs. Cardinals, and which side of the money line has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that's 49-37 on top-rated MLB picks, and find out.