The actress raised over $500,000 (£333,300) for Haiti relief organisations last year (10) by persuading famous friends to follow fans on Twitter.com in return for donations - and now she's campaigning for more cash.
In a video message posted online, the Desperate Housewives star urges fans to "make the world a better place".
This year (11), the actress is raising money for CARE, an organisation that helps young women globally.
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