Here are our top 8 most cited articles in 2024! What have you read in Cytotherapy that you expect to make top the list by the end of the year? Leukapheresis guidance and best practices for optimal chimeric antigen receptor T-cell manufacturing (https://lnkd.in/gPSWSnGy) Registered clinical trials investigating treatment with cell-derived extracellular vesicles: a scoping review (https://lnkd.in/gfYw9uHC) The NK-92 cell line-30 years later: its impact on natural killer cell research and treatment of cancer (https://lnkd.in/gxxhr-HY) Patient access to and ethical considerations of the application of the European Union hospital exemption rule for advanced therapy medicinal products #OpenAccess (https://lnkd.in/gKRfvpEH) Engineered exosome-mediated messenger RNA and single-chain variable fragment delivery for human chimeric antigen receptor T-cell engineering (https://lnkd.in/gKxqcThA) Adipose-derived stem cells applied in skin diseases, wound healing and skin defects: a review #OpenAccess (https://lnkd.in/g_mGpsVG) Dental pulp stem cell-derived extracellular matrix: autologous tool boosting bone regeneration (https://lnkd.in/gT6_QCR7) Prevention of chronic diabetic complications in type 1 diabetes by co-transplantation of umbilical cord mesenchymal stromal cells and autologous bone marrow: a pilot randomized controlled open-label clinical study with 8-year follow-up (https://lnkd.in/g2Q6zN3E)
Cytotherapy
Periodical Publishing
The Official Journal of ISCT: International Society for Cell & Gene Therapy
Über uns
2021 Impact Factor: 6.196 Cytotherapy, the official journal of the International Society of Cell and Gene Therapy (ISCT), publishes novel and innovative results from high quality scientific and clinical studies in the fields of cell and gene therapy. In addition to Short Reports and Full-Length Articles, the journal also accepts Editorials on emerging trends and potential controversies in the field, and Review articles summarizing important areas of cell and gene therapy research that are topical and/or challenge existing paradigms in the field. Cytotherapy considers manuscripts exploring the following topics: - Development and/or characterization of novel gene therapies and cell and/or EV-based therapeutics - Design of novel therapeutic approaches employing cell/EV/gene products. - Mode of action of cell/EV/gene therapies in relevant cell-based and pre-clinical models. - Identification of novel biomarkers that predict the potency of cell/EV/gene therapies and/or stratify patients based on response rates. - Role of stem/stromal cells and/or EVs in disease pathophysiology. - Early and late phase clinical studies evaluating the safety and efficacy of cell/EV/gene therapies. - Important advances in cell/EV/gene-based product manufacturing and validation - Global/regional regulatory practices that impact the authorized use and/or regulatory approval of cell/EV and gene therapies. Cytotherapy does not publish manuscripts on the following topics: - Case studies unless they are of unusual significance to the field. - Basic/translational studies exploring the role of lncRNAs, circRNAs, and miRNAs in disease pathophysiology - Studies describing signaling pathways implicated in cancer
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https://www.isct-cytotherapy.org/
External link for Cytotherapy
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Aktualisierungen
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Out now in the September issue of Cytotherapy: Process development for the production of mesenchymal stromal cell-derived extracellular vesicles in conventional 2D systems #OpenAccess #Exosomes (https://lnkd.in/g3dHE_TN) Substrate elasticity does not impact DNA methylation changes during differentiation of pluripotent stem cells #OpenAccess #StemCell (https://lnkd.in/g6UHFVj6) Adipose-derived stromal vascular fraction cells to treat long-term pulmonary sequelae of coronavirus disease 2019: 12-month follow-up #OpenAccess #StromalCell (https://lnkd.in/gfX9kbwa) Development of a robotic cluster for automated and scalable cell therapy manufacturing #OpenAccess #Manufacturing(https://lnkd.in/gaHTMGDG) You can view the full Table of Contents here: https://lnkd.in/gtDfSWUP Cover Image: Confocal image showing 3D printed GelMA laden H9C2 cells stained with phalloidin after 21 days of culture. Dr. KAVITHA GOVARTHANAN To have your image featured on the cover of a future issue of Cytotherapy, enter the #InstaYourCells competition! Submissions are open to ISCT members and non-members alike, and are open until October 31, 2024: https://lnkd.in/gjg94jZD
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Did you know that Cytotherapy cover images are sourced from the #ISCTInstaYourCells contest? Tag your colleagues who capture images that you want to see on the front of our Journal, and encourage them to submit to this year's contest! To learn how you can have your image featured on the cover of a future issue, follow the link below.
Mark your calendars and start collecting the best images from your lab. Get your cells ready, get creative, capture the beauty of your lab work and share it with the world! Content opens on August 19, 2024. Learn more: https://buff.ly/4cnsCvd
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In press this week, a case study on neurotoxicity associated with CAR T-cell re-expansion from Humanitas Research Hospital. chiara de philippis, A. Giacomel, U. Pensato, C. Pinton, D. Taurino, Daniele Mannina, Jacopo Mariotti, Barbara Sarina, simona marcheselli, Inna Timofeeva, R. Capizzuto, armando santoro, S. Bramanti https://lnkd.in/gM3Yt7wt
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New #OpenAccess article in press! Thong Teck Tan, Ruenn Chai Lai, Wei Kian Sim, Bin Zhang, and Sai Kiang Lim described a novel approach to extracellular vesicle modulation. Extracellular Modulation of Cells by EV (EMCEV) harnesses EV attributes to generate molecules that can influence multiple cells, eliciting a response beyond a single cell. Read more: https://lnkd.in/g2PPXEv7
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The August edition is here! In this issue: Current guidelines, challenges and future recommendations for regulation of stem cell research and therapy: a commentary (https://lnkd.in/gM3K2EAV) Neutrophil generation from hematopoietic progenitor cells and induced pluripotent stem cells (iPSCs): potential applications (https://lnkd.in/gpJY-auT) Treatment of post-allogeneic hematopoietic stem cell transplant cytopenias with sequential doses of multipotent mesenchymal stromal/stem cells (https://lnkd.in/gv4xhYG3) Synthetic biology approaches for enhancing safety and specificity of CAR-T cell therapies for solid cancers (https://lnkd.in/gw7DJitB) Check out the full Table of Contents here: https://lnkd.in/gwrXigea Cover Image: Whole tumor draining lymph node of a mouse with an established breast cancer tumor. Basic stains for Tertiary Lymphoid Structures (TLS) include B220 (b cells- red) and PNAd (high endothelial vessels- green). Violet Young
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In Press this week, Pauline De Berdt, Elodie Deltour, Eric Pauly, Noelia Gordillo, Frederic Lin, Etienne Sokal, MD, PhD, and Mustapha NAJIMI describe a #SerumFree protocol for the expansion of liver-derived progenitor cells. They demonstrate improved stability and reduced doubling time compared to serum-containing cultures. https://lnkd.in/gxZKFsrM
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Don’t miss your last chance to apply to the Innovation Zone Presentations at ISCT Europe 2024! This exclusive platform is designed for disruptive cell and gene therapy start-ups to showcase their groundbreaking technologies and elevate their corporate visibility. Selected applicants will receive a 10-minute presentation slot within the ISCT Europe Program, with the unique opportunity to receive direct feedback from a panel of industry experts including investors in the field. Apply now to claim one of our limited spaces! Applications close Friday, July 26, 2024. https://buff.ly/4eDCV0C
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Have you read our July issue yet? If you are looking for a place to start, check out this #OpenAccess publication that ISCT, International Society for Cell & Gene Therapy European Committee wrote in collaboration with The EBMT. The current challenges facing the translation of cell and gene therapies in Europe are explored, with recommendations on expanding registries for real-world assessment, the role of accreditation in protecting patients, and the importance of developing the sector's workforce are highlighted, among other key issues by Fermin Sanchez-Guijo, Joaquim Vives, Annalisa Ruggeri, Christian CHABANNON, Selim Corbacioglu, Harry Dolstra, Dominique FARGE, Nico Gagelmann, Claire Horgan, Jurgen Kuball, bénédicte Neven, Tuula Rintala, Vanderson Rocha, Isabel Sanchez-Ortega, Professor JOHN SNOWDEN, Jaap Jan Zwaginga, Massimiliano Gnecchi, Anna Sureda Balari. https://lnkd.in/geRErgZZ
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Now In Press, a new paper by Pedro Silva Couto, Dale Stibbs, Braulio Carrillo Sanchez, Rana Khalife, Theano Panagopoulou, PhD, Ben Barnes, Vaques George, PhD, Rouzbeh R. Taghizadeh, Ph.D., and Qasim Rafiq demonstrates a novel human #MSC line suited for suspension culture that provides a scalable platform for #manufacturing #EVs, enabling future studies. https://lnkd.in/gmtPd4vB
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