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    AIDS is a syndrome caused by the HIV virus which weakens the immune system. HIV is transmitted through bodily fluids and attacks T-cells. AIDS symptoms include weight loss, fever, tiredness, and neurological disorders. Several plants have been found to have anti-HIV properties, including Calophyllum lanigerum, Castanospermum australe, and Tripterygium wilfordii. These plants contain compounds that inhibit HIV's reverse transcriptase enzyme or prevent viral glycoprotein coating.

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    AIDS is a syndrome caused by the HIV virus which weakens the immune system. HIV is transmitted through bodily fluids and attacks T-cells. AIDS symptoms include weight loss, fever, tiredness, and neurological disorders. Several plants have been found to have anti-HIV properties, including Calophyllum lanigerum, Castanospermum australe, and Tripterygium wilfordii. These plants contain compounds that inhibit HIV's reverse transcriptase enzyme or prevent viral glycoprotein coating.

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    22 views6 pages

    Anti AIDS Herbs

    Uploaded by

    khansa maryam
    AIDS is a syndrome caused by the HIV virus which weakens the immune system. HIV is transmitted through bodily fluids and attacks T-cells. AIDS symptoms include weight loss, fever, tiredness, and neurological disorders. Several plants have been found to have anti-HIV properties, including Calophyllum lanigerum, Castanospermum australe, and Tripterygium wilfordii. These plants contain compounds that inhibit HIV's reverse transcriptase enzyme or prevent viral glycoprotein coating.

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    of 6

    1.

    AIDS (Acquired Immunodeficiency Syndrome)


     AIDS is a syndrome caused by a virus called HIV (human immunodeficiency virus).
    The disease alters the immune system, making people much more vulnerable to
    infections and diseases. This susceptibility worsens as the syndrome progresses.
     HIV is found throughout all the tissues of the body but is transmitted via the body
    fluids of an infected person (semen, vaginal fluids, blood, and breast milk).
     HIV is the virus, which attacks the T-cells of immune system. AIDS is the syndrome,
    which appears in the advanced stage of HIV infection.
     HIV is a virus.
     AIDS is a medical condition.

    1.1. Symptoms

     Rapid weight loss


     Recurring fever , night sweats
     Extreme and unexplained tiredness
     Diarrhea that lasts for more than a week
     Sores of the mouth, anus, or genitals
     Pneumonia
     Red, brown, pink, or purplish blotches on or under the skin or inside the mouth, nose,
    or eyelids
     Memory loss, depression, and other neurologic disorders

    1.2. Plants having Anti-HIV activity


    Following plants are reported to have anti HIV activities

    1.2.1. Calophyllum lanigerum


    1.2.1.1. Biological source
    Calophyllum lanigerum

    1.2.1.2. Family
    Calophyllaceae

    1.2.1.3. Part used


    Leaves and twigs of the tree

    1.2.1.4. Chemical constituents


    The calanolides, a novel HIV-inhibitory class of coumarin derivatives.

    Calanolide A

    1.2.1.5. Mode of Action


    Calanolide A represents a new pharmacological class of non-nucleoside ,HIV-1
    specific, Reverse transcriptase inhibitors.Reverse transcriptase is a viral enzyme
    essential for retroviruses to replicate, allowing viral RNA to serve as template for
    DNA synthesis prior to integrating into the host cell genome.Such RNA directed
    DNA synthesis does not occur in uninfected cells, therefore,reverse transcriptase
    activity is considered a unique function of the retrovirus. This enzyme present one
    of the most important targets for development of selective antiretroviral agents.
    1.2.1.6. Uses
     Calanolide A is an experimental compound obtained by Calophyllum
    lanigerum having Anti-HIV activity.
     HIV 1 Specific

    1.2.2. Castanospermum australe

    1.2.2.1. Biological source


    Catanospermum australe

    1.2.2.2. Common names


    Lucky beans plant

    1.2.2.3. Family
    Papilionaceae
    1.2.2.4. Part used
    Dried seeds

    1.2.2.5. Chemical constituents


    The seeds yields an alkaloid of the tetrahydroxy indolizidine group called
    castanospermine

    1.2.2.6. Mode of Action


    Castanospermine exerts its biological effects on insect larvae by inhibiting the
    carbohydrase enzymes which are essential for the elaboration of the
    oligosaccharides side chains of glycoproteins.This led to the testing of the
    alkaloid against HIV on the basis that as the compound inhibits of glycoproteins
    in the viral coat ,then without the essential envelope structure the virus would be
    unable to infect healthy white blood cell. Two other inhibitors of α-glucosidases
    inhibitors isolated from seeds of C.australe are 6-epi-castanospermine and
    tetrahydroxypyrrolizidine alkaloid australine

    1.2.2.7. Uses
     Anti-HIV activity
     Anti-inflammatory
     Anti-cancer

    1.2.3. Tripterygium wilfordii


    1.2.3.1. Biological source
    Tripterygium wilfordii

    1.2.3.2. Common names


    Thunder God vine

    1.2.3.3. Family
    Celastraceae

    1.2.3.4. Part Used


    Dried roots

    1.2.3.5. Chemical constituents


    Salaspermic acid (Pentacyclic triterpenoid), tripterifordin (diterpene lactone)

    Salaspermic acid
    1.2.3.6. Mode of action
    Reverse transcriptase is a viral enzyme essential for retroviruses to
    replicate,allowing viral RNA to serve as template for DNA synthesis prior to
    integrating into the host cell genome.Such RNA directed DNA synthesis does not
    occur in uninfected cells,therefore,reverse transcriptase activity is considered a
    unique function of the retrovirus.This enzyme present one of the most important
    targets for development of selective antiretroviral agents.

    1.2.3.7. Uses
     Salaspermic acid possess anti-HIV property
     Effective against Psoriasis
     Rheumatoid Arthritis
     Fever
     Swelling
     Regulates immune system

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