Ancy Lost Oma
Ancy Lost Oma
(Hook worm)
Presented
By
Dr. Maria Akhtar
Ancylostoma
Derived from two Greek words
Ankylos = Hook
Stoma =Mouth
Egg
Rhabditiform
larva
Adult
Morphology
Adults
♀+♂
Ancylostoma
duodenale
Adult Male & Female A.Duodenale
Adult Male A.Duodenale Worm
Copulatory bursa at
posterior end .
Smaller than the females
5-11mm in size
Adult Male A.Duodenale Worm
Ancylostoma duodenale
Chitinous
teeth plates
Scanning electron micrograph of the mouth capsule
of Ancylostoma duodenale, note the presence of
four "teeth," two on each side.
Ancylostoma duodenale
Eggs
Shape : oval with an empty space between the
shell and content
Size: 60 x 40 μm
Shell: Thin egg shell
Color: Colorless and transparent
Content: 4-8 cell unembryonated
Immature eggs pass in feces
(20,000 eggs ⁄ day).
Ancylostoma duodenale
Eggs
Transmission
Filariform juveniles wait in soil or
feces and wave back and forth to
increase chances of finding a host
Filariforms then penetrate the skin
(usually hands or feet)
Children, elderly people and people
who work about contaminated soil
are at high risk
Life Cycle and Reproduction
Eggs are passed in the feces and hatch into
rhabditiform larvae in about 48 hours in the
feces or in the soil
A. duodenale
Life cycle continued
Juveniles feed on feces for about 3 days
then molt into 2nd stage juveniles
They molt again 5-10 days later into
filariform larvae. Can survive 3-4 weeks
outside host.
Life Cycle
1-Invasion stage:
The skin, at the site of entry of filariform larva
Maculopapular lesions “ ground itch” or “dew itch”
Itching, edema.
3) Toxic substances .
-intestinal ulcers: flatulence, nausea, vomiting ,diarrhea.
Feeding hookworms
Albendazole
Drug of choice
Ovicidal and larvicidal
400 mg single dse in adults and children over 2
years old
Mebendazole
500 mg single dose in adults and children
Not recommended for children below 2 years old
Prevention
Wear shoes
Prevention and Control
Sanitary disposal of human faeces
Health education
Treatment of infected individuals
Scientist are trying to develop a
vaccine