Modern Blood Banking and Transfusion in Clinical Practice: Second Edition
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Hematology".
Deadline for manuscript submissions: 25 May 2025 | Viewed by 22
Special Issue Editor
Interests: blood transfusion; patient blood management; blood banking; immunohematology; cell therapy; transplantation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear colleagues,
Blood banking and blood component transfusion practices have improved considerably over the years. Some of the notable changes are the increasing automatization of compatibility testing and the implementation of electronic systems to monitor the transfusion process to record adverse effects; however, in the last decade blood banks have faced new problems. The use of monoclonal antibodies, such as anti-CD38 and anti-CD47, for the treatment of patients with malignancies is a concern, since these treatments produce interference with pretransfusion compatibility tests, delaying blood availability. In addition, the infusion of cell therapy products is carried out by blood bank staff in many countries. Therefore, blood banks must be on alert to provide a response to these new challenges in a timely manner.
Transfusion is one of the most widely used therapies, sometimes involving inappropriate episodes. Benefits and risks have to be carefully considered in each clinical situation when a blood transfusion is requested. Over the last decade hemovigilance systems have detected a decline in red blood cell usage, which could be explained in part by the incorporation of restrictive strategies based on current scientific evidence. In fact, patient blood management programs are being progressively incorporated into clinical practice in order to reduce unnecessary blood exposure and improve patient outcomes.
The aim of this Special Issue is to provide updates on the most relevant advances in blood banking laboratory and transfusion practise, focusing on those situations in which transfusion can be challenging, such as sickle cell disease, solid organ transplantation, massive transfusion, and cell therapy recipients, among others.
Dr. Pilar Solves
Guest Editor
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Keywords
- blood transfusion therapy
- patient blood management
- restrictive transfusion
- cell therapy
- platelet transfusion
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