B.Tech Biotechnology

• Curriculum Details

  The detailed curriculum will shed light on the navigation of programme throughout the duration of four years.
  • B.Tech. Biotechnology Curriculum 2022-26
  • B.Tech. Biotechnology Curriculum 2021-25
  • B.Tech. Biotechnology Curriculum 2020-24
  • B.Tech. Biotechnology Curriculum 2019-23
  • B.Tech. Biotechnology Curriculum 2018-22

• Minors

  Students can pursue Minor subjects from the 2nd year, i.e.,3rd semester onwards.

• Specialisations

  There are 5 Specializations are offered by Department of Biotechnology, namely: Biomedical Technologies, Drug Discovery & Protein Therapeutics, Genetic Counselling & Precision Medicine, Industrial Biotechnology, Nanotechnology & Biosensors

• Core Electives

  The Department provides core electives in Phytopharmaceuticals: Engineering & Production, Drug Design, and Discovery, Microbiome in Health & Disease, Personalized Medicine and Therapeutics, Biorefinery and Bioeconomy, among others

• Open Elective

  Students can choose open electives from 2nd year onwards, i.e., from 4th semester, and will carry 15 credits. These are the interdisciplinary courses that students can opt from different schools. Open Electives available from other departments: Linux Apache MySQL PHP (LAMP), Software Engineering, Numerical Methods, Introduction to Communication, Launch Your Startup, Personal Branding, Project Management, Constitutional Governance & RTI, Theories of Mass Communication, and Inside China: An Indian Perspective.

• Internships

  Project based learning through mini projects, summer internship, and Industrial R&D projects. Apart from on-campus research projects, students participate in summer internships from the very first year onwards but internships are mandatory in third year. The organizations where students went for internships are Centre of Biomedical Research - Lucknow, National Institute of Cholera and Enteric Diseases – Kolkata, HCL Infosystems, IIT Kanpur, Rapture Biotech-Lucknow, Shrii AMM Murugappa Chettiar Research Centre – Chennai, SeqIndia Labs, IIT Chennai, IIT Roorkee, IIT Kanpur, Department of Botany, University of Delhi, University of Nebraska, Omaha, USA, IIT BHU, IIT Delhi, IIT Roorkee, CSIR-IGIB, ICGEB, CDRI Lucknow, NCL Pune, Dabur Research Foundation, University of Hyderabad, Panacea Biotech, to name a few.

B.Tech. Biotech Specialisations

• Biomedical Technologies

  Biomedical Technology has provided invaluable tools for diagnosis and creating life-saving equipment. This specialization will have three courses:

  1. Biomedical Technologies in Diagnostics and Therapy: 3D Bioprinting, Artificial organs, electronic implants, biomaterials, biocompatibility, stem cells and tissue engineering, radiation oncology; biomedical devices: prefilled syringes, auto injectors, on body devices and pumps, skin patches, etc.
  2. Bioimaging: Magnetic resonance imaging, micro and nano tomography of biological tissues, image analysis, molecular imaging, data analytics towards diagnosis
  3. Medical Innovations: Ex-vivo immunotherapy, organs-on-chip, microbiome-based therapies, Case studies

• Drug Discovery & Protein Therapeutics

  This specialization focuses on understanding various drug discovery tools and methods used for finding, identifying, and designing a new drug and understanding the regulatory procedures for drug development.

  The three courses include following subjects:

  1. Drug Discovery Process and Molecular Basis: Natural products as pharmaceutical lead compounds, modern medicinal chemistry techniques, case studies on the development of a class of compounds, indicative areas are in antivirals, oncology and central nervous system diseases. Introduction to screening hits, and optimization of hits to reduce potential drug side effects (increasing affinity and selectivity), efficacy or potency, metabolic stability (half-life), and oral bioavailability
  2. Rational Drug Design and Structure Determination: Protein structure determination including crystallography, NMR and Cryo-EM, Structure visualization, homology modelling and docking, virtual screening for lead discovery, structure-based and ligand-based design methods and the use of computational techniques in library preparation and data handling
  3. Biotherapeutics: Modern therapeutic approaches, overview of antibody based therapeutics, biologics for autoimmunity and inflammation, genetically engineered vaccines, present and future biologics, principles of immunodiagnostic assay, development and clinical implementation of live biotherapeutic products and regulatory roadmaps

• Genetic Counselling & Precision Medicine

  Students interested in acquiring advanced expertise in applied genetics and genomics should opt for this specialization.

  Brief B.Tech Biotechnology syllabus for three courses include:

  1. Human Genetics: Human genes and genomes, Mendelian and Non-mendelian mode of inheritance, Mitochondrial inheritance, Genetics of complex and single gene disorders, genetic variations in health and disease, Hardy-Weinberg Equilibrium, Haplotypes and linkage studies, Diagnosis and Molecular basis of Cancer, Cardiovascular, Cardiometabolic diseases, Neurodegenerative disorders, Mitochondrial and rare disorders. Signal transduction and human diseases, Animal models of human diseases
  2. Genetic Counselling: Review of human genetics, pedigree analysis, Causes and factors for seeking counselling, risks evaluation, basics of embryology, dysmorphology, Risks associated with invasive procedures, Foetal sampling procedure, Analysing ultrasounds, therapeutic benefits of dietary management and various counselling approaches; Preconceptional counselling; Counselling recurrent pregnancy loss; pre – marital counselling. Ethical and legal issues in genetic counselling.
  3. Genomics and Personalized Medicine: Human Genome Mapping, Gene therapy with case studies and Gene editing tools, Genome wide association studies, Omics technologies in precision medicine, Nutrigenomics, Metabolomics, Microbiome fingerprinting, etc. Molecular Basis of Personalized Medicine, Polymorphisms of Drug Transporters, Drug Targets, Drug metabolizing enzymes, Ethical, Legal, and Social Issues related to Personalized Medicine, Personalized management of miscellaneous disorders.

• Industrial Biotechnology

  This specialization aims to provide advanced courses on green products ranging from enzymes and biocatalysts, biofuels, biobased platform chemicals, among others. The subjects covered under this specialization are:

  1. Enzyme Technology: Enzyme production, purification, and preservation. Enzyme immobilization techniques, Enzyme reactors and reaction kinetics, Improvement of enzyme activity and stability, Directed evolution of enzymes, Enzymes in food industries, Enzymes in pharmaceutical industries, Enzymes in bio-pharmaceutical industries, Enzymes in biochemical industries, Enzymes in textile and detergent industries, Enzymes in R&D, Case studies and current status of enzyme research, Global market of enzymes and opportunities for biotech professionals, Quality control of enzymes.
  2. Green Chemicals & Sustainable Products: Concept of sustainability and green chemicals, Carbon credit & carbon tax, Lifecycle analysis (LCA) & cost benefit analysis, Smart drop-in chemicals, Fossil based chemicals vs. biobased chemicals, Biobased bulk chemicals, Bio-platform chemicals, Specialty chemicals, Biobased fragrance and aroma compounds, Biobased active pharmaceutical ingredients (APIs) and high value products, Antibiotics production, Biobased steroids & derivatives, Bioplastics and polymers, Biodegradable vs. non-biodegradable bioplastics, Natural vs. synthetic biopolymers, Final products manufactured using green chemicals, Case studies of industrial production of green chemicals, and current status of green chemicals research.
  3. Biofuels & Biorefinery: Biomass & bioenergy, Production and purification of bioethanol, Biodiesel production, Biobutanol, Biogas & Bio-CNG, Biohydrogen, Microbial fuel cell, Bio-aviation fuels, Biofuel production under biorefinery framework, Algal biorefinery for high value compounds, Biorefinery for high value secondary metabolites, Extraction and purification of high value phytochemicals under biorefinery framework, Biofuel production and simultaneous waste management, Metabolic engineering for biofuel production, Biofuel production process simulation, Scale-up of biofuel production processes, Case studies of biofuel production, and current status of biofuel research and job opportunities.

• Nanotechnology & Biosensors

  This specialization is best suited for students who want to deep dive into subjects of nanotechnology, the uses of nanomaterial in biosensors, and wearable technology. BTech Biotechnology syllabus of 3 subjects which will be covered during this specialization are:

  1. Nanomedicine: Principles and concepts, Development of nanoparticles/ liposomes/ lipid nanoparticles/ micelles, Surface modification, Characterization, Encapsulation, Release kinetics, Cargo- Drug/ gene/ protein/ antibody etc. Cellular and physiological barriers. Clinical Applications in different disease
  2. Introduction to Biosensors and Bioelectronics: Thermal and electronic biosensors, Optical biosensors, Mechanical biosensors: microfluidics – basic introduction to basic microfluidic concepts. Fabrication, characterization and detection of bioanalyte. Live sensors, Applications- clinical and non-clinical (defense/ Agriculture/ Pollution). Regulatory aspects. Commercialization examples.
  3. Digital healthcare, Theranostics and Lab-on-a-chip: Digital and mobile healthcare: wearable devices – commercial needs and contexts. Principles, Design, Preparation, Delivery mechanism, Imaging modality, Metallic nanoparticles, Photothermal Therapy/ Radiation Therapy/ MRI/ CT/ PET, Clinical Applications. Lab-on-a-chip sensing - device type, sample preparation, and readouts; Organ-on-a-chip – principles and applications. Regulatory aspects. Commercialization examples.