Financial Economics

Importance. Medication-induced eosinophilia is an acknowledged, often self-limiting occurrence. Glatiramer acetate, a biologic injection used in the management of relapsing-remitting multiple sclerosis, is widely regarded as a safe and effective medication and lists eosinophilia as an infrequent side effect in its package insert. Contrary to reports of transient, benign drug-induced eosinophilia, we describe a case of probable glatiramer acetate-induced eosinophilia that ultimately culminated in respiratory distress, shock, and eosinophilic myocarditis. Observations. A 59-year-old female was admitted to the hospital after routine outpatient labs revealed leukocytosis (43,000 cells/mm(3)) with pronounced hypereosinophilia (63%). This patient had been using glatiramer acetate without complication for over 10 years prior to admission. Leukocytosis and hypereosinophilia persisted as a myriad of diagnostic evaluations returned negative, ultimately leading to respiratory depression, shock...

With the passage of time, there has been a drastic increase in psychiatric disorders in past few decades across the world. Due to lack of education and awareness in the rural community, a majority of people still have strong misconceptions about the causation of psychiatric disorders and hence serve as a barrier for their medical treatment. A comparative cross-sectional study was conducted in the urban and rural areas of Rawalpindi district from March to August 2015, to find out the perception about treatment of psychiatric disorders among general public. Structured closed ended questionnaire was used to collect data from the participants and the results were analysed using SPSS. Chi square test was used to determine the association between categorical variables among urban and rural areas. The finding of our study confirmed that people of urban areas tend to choose and seek treatment by psychiatrists more (74%) as compared to those living in rural area that tends to select and beli...

In the modern era, chewable tablets are preferred over conventional dosage forms by pediatric, geriatric and bedridden patients due to difficulty in swallowing, lesser amount of water for swallowing medications as well as unable to tolerate the bitter taste of certain drugs. Chewable tablets of Desloratadine (DS) were formulated by aqueous and non-aqueous granulation method using water paste and Isopropyl alcohol (IPA) as a wetting agents respectively. Desloratadine is used to treat the symptoms of allergy such as sneezing, watery eyes. In the recent research, we have formulated eight trials by various concentrations of excipients. For instance; lactose, talcum, magnesium stearate, blue color, flavor, aspartame, mannitol, avicel 101 and polyvenylpyrollidine (PVP). Pre-compression and post compression parameters (thickness, hardness, friability weight variation and drug content) of the formulations were evaluated. B3 was our optimum dosage form because its Hausner’s ratio, compressib...

The effect of N content on the characteristics and formation of inclusions in the Fe-5Mn-3Al steels was investigated in this study. Two synthetic steel melts were produced by two different methods—N2 gas purging and injecting—to introduce nitrogen into the melt. The N content of steel melt varied from 2 to 54 ppm. An increase in the N content to 47 ppm (for 533N-P) and 58 ppm (for 533N-I) increased the total amount of inclusions from 13 to 64 mm−2 and from 21 to 101 mm−2, respectively. The observed inclusions were Al2O3(pure), Al2O3-MnS, AlN(pure), AlN-MnS, AlON, AlON-MnS, and MnS. When the N content was less than 10 ppm, AlN-MnS inclusions were the primary type of inclusions and they formed as solidification products. With an increase in the N content, AlN(pure) inclusions became the dominant type of inclusions as AlN was stable in the liquid steel. These findings were confirmed by thermodynamic calculations. The influence of cooling rate on the types of inclusions was studied and ...

This study focused on the characteristics of complex MnS inclusions in advanced high strength steels. The effect of metal chemistry (Al and N) and the cooling rate of steel were evaluated by analyzing the inclusions present in five laboratory produced steels. The observed complex MnS inclusions contained Al2O3-MnS, AlN-MnS, and AlON-MnS. An increase in Al content from 0.5% to 6% increased the number of complex MnS inclusions by ~4 times. In comparison, a decrease of ~80% was observed due to the increased N content of steel from <10 ppm to ~50 ppm. MnS precipitation ratio was used to determine the potency of different inclusions forming complex MnS inclusions due to heterogeneous nucleation. It was found that the MnS precipitation ratio of the observed inclusions was related to their misfit with MnS, and it decreased in the order of AlN > AlON > Al2O3. Moreover, it was determined that AlN particles could be easily engulfed at the solidification front relative to Al2O3, which...

Background: To compare the hemodynamicchanges during induction of anesthesia withpropofol and sevoflurane in children undergoingforearm orthopedic surgeries.Methods: In this descriptive study 60 pediatricpatients, scheduled for forearm orthopedic surgicalprocedure under general anesthesia requiring LMAinsertion were included. The selected patients wereallocated into two groups; A (Propofol) and B(Sevoflurane) of 30 each. Group A was induced withIV Propofol 2mg/kg while Group B was induced bysevoflurane 6-8%. Anesthetic induction wassupposedly achieved after loss of eyelash reflex.Results: Compared with base line, both groupsshowed a statistically significant decline in meanarterial pressure after induction. Propofol group (A)showed a larger transient decrease in MAP comparedto sevoflurane group (B) (p<0.001). There was astatistical significant overall greater decline in MAPand heart rate after induction with propofol whencompared with sevoflurane.Conclusion: Sevoflurane provides ...

Purpose:-The basic aim of this research is to examine liquidity management impact on profitability in banking sector of Pakistan. Methodology: The secondary data used for this study and taking from publish annual report of ten banks (2006-2015). The data was analyzed by using correlation, descriptive statistics and regression techniques run on E-views. The quick, current, cash, interest coverage and capital adequacy ratios are taken as dimension of liquidity and return on asset, return on equity, and earning per share as dimension of profitability. Findings: The research finding shows that quick and capital adequacy ratio has positive impact on banks profitability determinants earnings per share and return on assets. The cash and current ratio has a negative relationship with return on assets. While interest coverage ratio is positively associated with return equity and earnings per share and is negatively associated with return on equity. Therefore overall empirical results show th...

The ETSI has recently introduced the DECT-2020 New Radio (NR) as an IMT-2020 candidate technology for the mMTC and URLLC use cases. To consider DECT-2020 NR as an IMT-2020 technology, the ITU-R has determined different independent evaluation groups to assess its performance against the IMT-2020 requirements. These independent evaluation groups are now in process of investigating the DECT-2020 NR. In order to successfully assess a technology, one important aspect is to fully understand the underlying physical layer and its performance in different environments. Therefore, in this paper, we focus on the physical layer of DECT-2020 NR and investigate its link-level performance with standard channel models provided by the ITUR for evaluation. We perform extensive simulations to analyze the performance of DECT-2020 NR for both URLLC and mMTC use cases. The results presented in this work are beneficial for the independent evaluation groups and researchers as these results can help calibra...

University students are a sub-group of the population at high risk of COVID-19 infection, and their judgments on vaccination affect the public attitudes towards vaccination. Thus, the present study aimed to assess the knowledge, attitudes, perceptions, and acceptance of the COVID-19 vaccine among pharmacy and non-pharmacy students. A cross-sectional study was conducted by enrolling pharmacy (375) and non-pharmacy (225) students from the universities in Lahore. Chi-square analysis was used for significant frequency distributions and a 5-point Likert scale was used to score attitude, perception, and acceptance. The majority of the students were aged between 19–24 years, hailing from urban and middle-class families with good self-reported health. The preferred vaccine was Pfizer, followed by Sinopharm and Sinovac. The major source of information was social media, followed by government campaigns and family members. The pharmacy students demonstrated better knowledge and positive attitu...