Paucity and discordance of neutralising antibody responses to SARS-CoV-2 VOCs in vaccinated immunodeficient patients and health-care workers in the UK

Lancet Microbe. 2021 Sep;2(9):e416-e418. doi: 10.1016/S2666-5247(21)00157-9. Epub 2021 Jun 28.

Authors

Angalee Nadesalingam¹, Diego Cantoni², David A Wells¹, Ernest T Aguinam¹, Matteo Ferrari¹, Peter Smith¹, Andrew Chan¹, George Carnell¹, Luis Ohlendorf¹, Sebastian Einhauser³, Charlotte George¹, Ralf Wagner^{4

3}, Nigel Temperton², Javier Castillo-Olivares¹, Helen Baxendale⁵, Jonathan L Heeney¹; HICC consortium

Affiliations

¹ Laboratory of Viral Zoonotics, University of Cambridge, Cambridge CB3 OES, UK.
² Viral Pseudotype Unit, Medway School of Pharmacy, University of Kent, Medway, UK.
³ Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany.
⁴ Institute of Clinical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany.
⁵ Clinical Immunology Department, Royal Papworth NHS Foundation Trust, Cambridge, UK.

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antibodies, Neutralizing / therapeutic use
Antibodies, Viral
COVID-19* / prevention & control
Humans
SARS-CoV-2*
United Kingdom / epidemiology

Substances

Antibodies, Neutralizing
Antibodies, Viral