Ras-related protein R-Ras2 is a protein that in humans is encoded by the RRAS2 gene.[5][6][7]

RRAS2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRRAS2, TC21, related RAS viral (r-ras) oncogene homolog 2, RAS related 2, NS12
External IDsOMIM: 600098; MGI: 1914172; HomoloGene: 6945; GeneCards: RRAS2; OMA:RRAS2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_012250
NM_001102669
NM_001177314
NM_001177315

NM_025846

RefSeq (protein)

NP_001096139
NP_001170785
NP_001170786
NP_036382

NP_080122

Location (UCSC)Chr 11: 14.28 – 14.36 MbChr 7: 113.65 – 113.72 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

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RRAS2 has been shown to interact with C-Raf.[8][9]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000133818Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000055723Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Drivas GT, Shih A, Coutavas E, Rush MG, D'Eustachio P (May 1990). "Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line". Mol Cell Biol. 10 (4): 1793–8. doi:10.1128/mcb.10.4.1793. PMC 362288. PMID 2108320.
  6. ^ Chan AM, Miki T, Meyers KA, Aaronson SA (September 1994). "A human oncogene of the RAS superfamily unmasked by expression cDNA cloning". Proc Natl Acad Sci U S A. 91 (16): 7558–62. Bibcode:1994PNAS...91.7558C. doi:10.1073/pnas.91.16.7558. PMC 44441. PMID 8052619.
  7. ^ "Entrez Gene: RRAS2 related RAS viral (r-ras) oncogene homolog 2".
  8. ^ Li W, Han M, Guan K L (April 2000). "The leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and Raf". Genes Dev. 14 (8). UNITED STATES: 895–900. doi:10.1101/gad.14.8.895. ISSN 0890-9369. PMC 316541. PMID 10783161.
  9. ^ Movilla N, Crespo P, Bustelo X R (October 1999). "Signal transduction elements of TC21, an oncogenic member of the R-Ras subfamily of GTP-binding proteins". Oncogene. 18 (43). ENGLAND: 5860–9. doi:10.1038/sj.onc.1202968. ISSN 0950-9232. PMID 10557073. S2CID 31576945.

Further reading

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