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60S ribosomal protein L29

From Wikipedia, the free encyclopedia
RPL29
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRPL29, HIP, HUML29, RPL29P10, RPL29_3_370, ribosomal protein L29
External IDsOMIM: 601832; MGI: 99687; HomoloGene: 133570; GeneCards: RPL29; OMA:RPL29 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000992

NM_009082
NM_001324533
NM_001324534

RefSeq (protein)

NP_000983

NP_001311462
NP_001311463
NP_033108

Location (UCSC)Chr 3: 51.99 – 52 MbChr 9: 106.31 – 106.31 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

60S ribosomal protein L29 is a protein that in humans is encoded by the RPL29 gene.[5][6]

Function

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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L29E family of ribosomal proteins. The protein is also a peripheral membrane protein expressed on the cell surface that directly binds heparin. Although this gene was previously reported to map to 3q29-qter, it is believed that it is located at 3p21.3-p21.2. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[6]

Interactions

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RPL29 has been shown to interact with BLMH.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000162244Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000048758Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Law PT, Tsui SK, Lam WY, Luk SC, Hwang DM, Liew CC, Lee CY, Fung KP, Waye MM (Apr 1996). "A novel cDNA encoding a human homologue of ribosomal protein L29". Biochim Biophys Acta. 1305 (3): 105–8. doi:10.1016/0167-4781(95)00224-3. PMID 8597591.
  6. ^ a b "Entrez Gene: RPL29 ribosomal protein L29".
  7. ^ Koldamova RP, Lefterov IM, DiSabella MT, Almonte C, Watkins SC, Lazo JS (Jun 1999). "Human bleomycin hydrolase binds ribosomal proteins". Biochemistry. 38 (22): 7111–7. doi:10.1021/bi990135l. PMID 10353821.

Further reading

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  • Overview of all the structural information available in the PDB for UniProt: P47914 (60S ribosomal protein L29) at the PDBe-KB.