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ACTR3B

From Wikipedia, the free encyclopedia
ACTR3B
Identifiers
AliasesACTR3B, ARP11, ARP3BETA, ARP3 actin-related protein 3 homolog B (yeast)
External IDsMGI: 2661120; HomoloGene: 4180; GeneCards: ACTR3B; OMA:ACTR3B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001040135
NM_020445

NM_001004365
NM_001310504

RefSeq (protein)

NP_001004365
NP_001297433

Location (UCSC)n/aChr 5: 25.96 – 26.06 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Actin-related protein 3B also known as ARP3-beta is a protein that in humans is encoded by the ACTR3B gene.[4] Pseudogenes of this gene are located on chromosomes 2, 4, 10, 16, 22 and Y. Alternative splicing results in multiple transcript variants and protein isoforms.[4]

Function

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This gene encodes a member of the actin-related proteins (ARP), which form multiprotein complexes and share 35-55% amino acid identity with conventional actin. The protein encoded by this gene may have a regulatory role in the actin cytoskeleton and induce cell-shape change and motility.[4]

References

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  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000056367Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ a b c "Entrez Gene: ACTR3B ARP3 actin-related protein 3 homolog B (yeast)".
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Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.