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Ateronon

From Wikipedia, the free encyclopedia

Ateronon is a nutraceutical composed of lactolycopene, a combination of lycopene from tomato oleoresin and a whey protein matrix which increases the absorption / bioavailability of lycopene.[1][2]

A report containing data on Ateronon was presented at the British Cardiovascular Society Conference in June 2014.[3]

Studies

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LactoLycopene has been used in numerous studies focused on lycopene bioavailability. A University of Cambridge study shows that lycopene levels in the blood rose between 60% and 100% within two months for people taking LactoLycopene, while another study at Boston's Brigham & Women's Hospital, run by Harvard Medical School, found that it increased average blood levels of lycopene at both six and 12 months.[4]

It has also been used to investigate the effects of lycopene on heart function [5][6] and male fertility.

A study at the Cleveland Clinic found that lycopene can boost sperm quality by up to 70 per cent,[7] while a team of researchers at the University of Sheffield found that LactoLycopene supplementation significantly increases the percentage of fast progressive sperm as well as normal and healthy sperm forms.[8]

History

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Ateronon was developed by Cambridge Theranostics Ltd, UK, and launched in 2009.[9] The patent is currently held by its successor company, FutureYou Cambridge.

References

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  1. ^ Richelle M, Bortlik K, Liardet S, et al. (March 2002). "A food-based formulation provides lycopene with the same bioavailability to humans as that from tomato paste". J. Nutr. (Clinical trial). 132 (3): 404–8. doi:10.1093/jn/132.3.404. PMID 11880563.
  2. ^ Blume-Peytavi U, Rolland A, Darvin ME, et al. (September 2009). "Cutaneous lycopene and beta-carotene levels measured by resonance Raman spectroscopy: high reliability and sensitivity to oral lactolycopene deprivation and supplementation". Eur J Pharm Biopharm (Clinical trial). 73 (1): 187–94. doi:10.1016/j.ejpb.2009.04.017. PMID 19442725.
  3. ^ "Ateronon briefing sponsored symposium at the British Cardiovascular Society Annual Conference" (PDF). June 2014. Retrieved 2014-06-03.
  4. ^ Karppi J, Laukkanen JA, Sivenius J, Ronkainen K, Kurl S (September 2009). "Serum lycopene decreases the risk of stroke in men". Neurology (Clinical trial). 73 (1): 187–94. doi:10.1212/WNL.0b013e31826e26a6. PMID 23045517. S2CID 29290243.
  5. ^ Gajendragadkar PR, Hubsch A, Mäki-Petäjä KM, Serg M, Wilkinson IB, Cheriyan J (June 2014). "Effects of Oral Lycopene Supplementation on Vascular Function in Patients with Cardiovascular Disease and Healthy Volunteers: A Randomised Controlled Trial". PLOS ONE (Clinical trial). 9 (6): e99070. Bibcode:2014PLoSO...999070G. doi:10.1371/journal.pone.0099070. PMC 4049604. PMID 24911964.
  6. ^ Karppi J, Laukkanen JA, Sivenius J, Ronkainen K, Kurl S (October 2012). "Serum lycopene decreases the risk of stroke in men". Neurology (Clinical trial). 79 (15): 1540–1547. doi:10.1212/WNL.0b013e31826e26a6. PMID 23045517. S2CID 29290243.
  7. ^ Durairajanayagam D, Agarwal A, Ong C, Prashast P (March 2014). "Lycopene and male infertility". Asian Journal of Andrology (Clinical trial). 16 (3): 420–425. doi:10.4103/1008-682X.126384. PMC 4023371. PMID 24675655.
  8. ^ Williams EA, Parker M, Robinson A, et al. (September 2019). "A randomized placebo-controlled trial to investigate the effect of lactolycopene on semen quality in healthy males". European Journal of Nutrition (Clinical trial). 59 (2): 825–833. doi:10.1007/s00394-019-02091-5. PMC 7058571. PMID 31591650.
  9. ^ "Tomato pill 'beats heart disease'". BBC News. 1 June 2009. Retrieved 2017-02-12.