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DHX34

From Wikipedia, the free encyclopedia
DHX34
Identifiers
AliasesDHX34, DDX34, HRH1, DEAH-box helicase 34, DExH-box helicase 34
External IDsOMIM: 615475; MGI: 1918973; HomoloGene: 69171; GeneCards: DHX34; OMA:DHX34 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014681
NM_194428

NM_001285931
NM_001285932
NM_027883

RefSeq (protein)

NP_055496

NP_001272860
NP_001272861
NP_082159

Location (UCSC)Chr 19: 47.35 – 47.38 MbChr 7: 15.93 – 15.96 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

DExH-box helicase 34 is a protein that in humans is encoded by the DHX34 gene. [5]

Function

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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. It is mapped to the glioma 19q tumor suppressor region and is a tumor suppressor candidate gene. [provided by RefSeq, Jul 2008].

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000134815Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000006019Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: DExH-box helicase 34". Retrieved 2018-03-21.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.