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DVL3

From Wikipedia, the free encyclopedia
DVL3
Identifiers
AliasesDVL3, DRS3, dishevelled segment polarity protein 3
External IDsOMIM: 601368; MGI: 108100; HomoloGene: 20928; GeneCards: DVL3; OMA:DVL3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004423

NM_007889
NM_001347176

RefSeq (protein)

NP_004414

NP_001334105
NP_031915

Location (UCSC)Chr 3: 184.16 – 184.17 MbChr 16: 20.34 – 20.35 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Segment polarity protein dishevelled homolog DVL-3 is a protein that in humans is encoded by the DVL3 gene.[5][6]

This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation.[6]

Interactions

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DVL3 has been shown to interact with DAB2,[7] DVL1[8] and PRPF3.[9]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000161202Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000003233Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Pizzuti A, Amati F, Calabrese G, Mari A, Colosimo A, Silani V, Giardino L, Ratti A, Penso D, Calza L, Palka G, Scarlato G, Novelli G, Dallapiccola B (January 1997). "cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene". Hum Mol Genet. 5 (7): 953–958. doi:10.1093/hmg/5.7.953. PMID 8817329.
  6. ^ a b "Entrez Gene: DVL3 dishevelled, dsh homolog 3 (Drosophila)".
  7. ^ Hocevar, B A; Mou F; Rennolds J L; Morris S M; Cooper J A; Howe P H (June 2003). "Regulation of the Wnt signaling pathway by disabled-2 (Dab2)". EMBO J. 22 (12). England: 3084–3094. doi:10.1093/emboj/cdg286. ISSN 0261-4189. PMC 162138. PMID 12805222.
  8. ^ Kishida, S; Yamamoto H; Hino S; Ikeda S; Kishida M; Kikuchi A (June 1999). "DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability". Mol. Cell. Biol. 19 (6). UNITED STATES: 4414–4422. doi:10.1128/mcb.19.6.4414. ISSN 0270-7306. PMC 104400. PMID 10330181.
  9. ^ Rual, Jean-François; Venkatesan Kavitha; Hao Tong; Hirozane-Kishikawa Tomoko; Dricot Amélie; Li Ning; Berriz Gabriel F; Gibbons Francis D; Dreze Matija; Ayivi-Guedehoussou Nono; Klitgord Niels; Simon Christophe; Boxem Mike; Milstein Stuart; Rosenberg Jennifer; Goldberg Debra S; Zhang Lan V; Wong Sharyl L; Franklin Giovanni; Li Siming; Albala Joanna S; Lim Janghoo; Fraughton Carlene; Llamosas Estelle; Cevik Sebiha; Bex Camille; Lamesch Philippe; Sikorski Robert S; Vandenhaute Jean; Zoghbi Huda Y; Smolyar Alex; Bosak Stephanie; Sequerra Reynaldo; Doucette-Stamm Lynn; Cusick Michael E; Hill David E; Roth Frederick P; Vidal Marc (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062). England: 1173–1178. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

Further reading

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