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OR12D2

From Wikipedia, the free encyclopedia
OR12D2
Identifiers
AliasesOR12D2, DJ994E9.8, HS6M1-20, olfactory receptor family 12 subfamily D member 2 (gene/pseudogene), olfactory receptor family 12 subfamily D member 2
External IDsMGI: 2177484; HomoloGene: 133728; GeneCards: OR12D2; OMA:OR12D2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_013936

NM_146834

RefSeq (protein)

NP_039224

NP_667045

Location (UCSC)Chr 6: 29.4 – 29.4 MbChr 17: 37.61 – 37.62 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor, family 12, subfamily D, member 2, also known as OR12D2, is a protein which in humans is encoded by the OR12D2 gene.[5]

Function

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Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000280236Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000092077Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: OR12D2 olfactory receptor, family 12, subfamily D, member 2".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.