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SNX26

From Wikipedia, the free encyclopedia
ARHGAP33
Identifiers
AliasesARHGAP33, NOMA-GAP, SNX26, TCGAP, Rho GTPase activating protein 33
External IDsOMIM: 614902; MGI: 2673998; HomoloGene: 76448; GeneCards: ARHGAP33; OMA:ARHGAP33 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001172630
NM_052948
NM_001366178

NM_001289670
NM_001289682
NM_178252

RefSeq (protein)

NP_001166101
NP_443180
NP_001353107

NP_001276599
NP_001276611
NP_839983

Location (UCSC)Chr 19: 35.77 – 35.79 MbChr 7: 30.52 – 30.54 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

TC10/CDC42 GTPase-activating protein is an enzyme that in humans is encoded by the SNX26 gene.[5][6][7]

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The specific function of this protein has not been elucidated. Alternative splice variants have been described but their full length nature has not been determined.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000004777Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000036882Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Peck J, Douglas G IV, Wu CH, Burbelo PD (Sep 2002). "Human RhoGAP domain-containing proteins: structure, function and evolutionary relationships". FEBS Lett. 528 (1–3): 27–34. doi:10.1016/S0014-5793(02)03331-8. PMID 12297274. S2CID 30443852.
  6. ^ Worby CA, Dixon JE (Dec 2002). "Sorting out the cellular functions of sorting nexins". Nat Rev Mol Cell Biol. 3 (12): 919–31. doi:10.1038/nrm974. PMID 12461558. S2CID 36361630.
  7. ^ a b "Entrez Gene: SNX26 sorting nexin 26".

Further reading

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