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Sulfoacetaldehyde acetyltransferase

From Wikipedia, the free encyclopedia
sulfoacetaldehyde acetyltransferase
Identifiers
EC no.2.3.3.15
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a sulfoacetaldehyde acetyltransferase (EC 2.3.3.15) is an enzyme that catalyzes the chemical reaction

acetyl phosphate + sulfite 2-sulfoacetaldehyde + phosphate

Thus, the two substrates of this enzyme are acetyl phosphate and sulfite, whereas its two products are 2-sulfoacetaldehyde and phosphate.

This enzyme belongs to the family of transferases, specifically those acyltransferases that convert acyl groups into alkyl groups on transfer. The systematic name of this enzyme class is acetyl-phosphate:sulfite S-acetyltransferase (acyl-phosphate hydrolysing, 2-oxoethyl-forming). This enzyme is also called Xsc. This enzyme participates in taurine and hypotaurine metabolism.

References

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  • Ruff J, Denger K, Cook AM (2003). "Sulphoacetaldehyde acetyltransferase yields acetyl phosphate: purification from Alcaligenes defragrans and gene clusters in taurine degradation". Biochem. J. 369 (Pt 2): 275–85. doi:10.1042/BJ20021455. PMC 1223080. PMID 12358600.