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T-cell activation RhoGTPase activating protein

From Wikipedia, the free encyclopedia
TAGAP
Identifiers
AliasesTAGAP, ARHGAP47, IDDM21, TAGAP1, FKSG15, T-cell activation RhoGTPase activating protein, T cell activation RhoGTPase activating protein
External IDsOMIM: 609667; MGI: 3615484; HomoloGene: 44943; GeneCards: TAGAP; OMA:TAGAP - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_152133
NM_001278733
NM_054114
NM_138810

NM_145968

RefSeq (protein)

NP_001265662
NP_473455
NP_620165
NP_687034

NP_666080

Location (UCSC)Chr 6: 159.03 – 159.05 MbChr 17: 8.14 – 8.15 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

T-cell activation RhoGTPase activating protein is a protein that in humans is encoded by the TAGAP gene. [5]

Function

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This gene encodes a member of the Rho GTPase-activator protein superfamily. The encoded protein may function as a Rho GTPase-activating protein. Alterations in this gene may be associated with several diseases, including rheumatoid arthritis, celiac disease, and multiple sclerosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms.

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000164691Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033450Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: T-cell activation RhoGTPase activating protein". Retrieved 2017-09-10.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.