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TRIM9

From Wikipedia, the free encyclopedia
TRIM9
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTRIM9, RNF91, SPRING, tripartite motif containing 9
External IDsOMIM: 606555; MGI: 2137354; HomoloGene: 9045; GeneCards: TRIM9; OMA:TRIM9 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015163
NM_052978

RefSeq (protein)

NP_055978
NP_443210

Location (UCSC)Chr 14: 50.98 – 51.1 MbChr 12: 70.29 – 70.39 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Tripartite motif-containing protein 9 is a protein that in humans is encoded by the TRIM9 gene.[5][6][7]

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternate splicing of this gene generates two transcript variants encoding different isoforms.[7]

Interactions

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TRIM9 has been shown to interact with SNAP-25.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000100505Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021071Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, Riganelli D, Zanaria E, Messali S, Cainarca S, Guffanti A, Minucci S, Pelicci PG, Ballabio A (May 2001). "The tripartite motif family identifies cell compartments". EMBO J. 20 (9): 2140–51. doi:10.1093/emboj/20.9.2140. PMC 125245. PMID 11331580.
  6. ^ a b Li Y, Chin LS, Weigel C, Li L (Oct 2001). "Spring, a novel RING finger protein that regulates synaptic vesicle exocytosis". J Biol Chem. 276 (44): 40824–33. doi:10.1074/jbc.M106141200. PMID 11524423.
  7. ^ a b "Entrez Gene: TRIM9 tripartite motif-containing 9".

Further reading

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