Talk:Praziquantel
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The picture link was not working. I added a new picture of the praziquantel molecule.
Update
[edit]Dear Sir,
Is there any recent or latest updates on this product?because in your article prazequatil is only restricted to vaternary use and mentioned as until 2005.so is this drug is now approved for human use?
Thanks and regards,
Ram TAIBA PHARMA. MUSCAT. —The preceding unsigned comment was added by 85.154.11.37 (talk) 09:52, 19 February 2007 (UTC).
- Human use has long since been approved. See this web page for the basics: http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000474/ KDS4444Talk 23:25, 26 March 2012 (UTC)
- I suggest that this article is now too focused on use in humans - or at least no longer much explicit reference to its use in cats, dogs, and other domesticated animals. If treatment and reactions are the same between species (which I seriously doubt based on my personal experience administering drontal medication to my three cats and the advice from my veterinarian), then that needs to be stated; if not, then the differences should be noted in the article.Penelope Gordon (talk) 08:51, 10 May 2015 (UTC)
"Uses" section overhaul, 2012
[edit]I have recently completed an overhaul of the section now called "Uses" (don't really like that word... "Applications"? "Treatments"?) which describes the various ways prazinquatel gets applied to remove hemliths. I have structured the section with some care: the subsections are organized by named illnesses, then a brief word about the organism that causes the illness, and then, when readily available, a citation to corroborate the statement. Note that the name for an illness is often very similar to the name of the organism that causes it, but that they are medically considered distinct if obviously connected events. The section ends up sounding somewhat technical, and I am certain it is still not comprehensive (!), but its format is now consistent (at last) and the phrasing seems encyclopedic in its concision. I hope that future editors will consider my intentions in this section before any major structural revisions (which, if you have a better idea about how to present all this, would be fantastic!) KDS4444Talk 23:38, 26 March 2012 (UTC)
You could use an open access paper I recently wrote (now included in the main article) which has an introduction with a number of references about human use: The DOI for the paper is 10.1371/journal.pntd.0001260.--Latimer741 (talk) 14:05, 5 May 2012 (UTC)
What is the toxicity of Praziquantel?
[edit]The article as is is very useful but some information on the above I believe would improve it significantly. Cheers. — Preceding unsigned comment added by 220.233.22.24 (talk) 06:44, 30 May 2013 (UTC)
Toxocariasis
[edit]Praziquantel#Medical uses states that praziquantel is used to treat "toxocariasis in cats and dogs", and it's "often combined with pyrantel". Here is the first revision of that statement.
AFAIK, praziquantel is active against flatworms only, while toxocaras are roundworms; therefore, it's effectiveness per se against that disease is very unlikely. Regarding the use of combination drugs (e. g., mixtures of praziquantel with pyrantel or other anti-nematodal-only agents), the obvious reason is to treat possible multiple infections with a single medication. In the case of praziquantel-pyrantel combination used against toxocariasis, apparently, the active ingredient is pyrantel, while praziquantel remains idle.
So I suggest removing this and similar (see "feline taeniasis") ambiguous statements in the article section and adding something like this at the end: "To treat multiple infections, praziquantel is sometimes combined with other anthelmintic drugs: pyrantel, ivermectin, albendazole etc." --Djadjko (talk) 00:15, 9 September 2015 (UTC)
Hijacked reference
[edit]Reference No. 5 - Global pricing of Praziquantel - has been hijacked by an agent attempting to get the reader's personal information. I don't know how to correct this so I am posting in the hope that a more expert reader will deal with this issue. — Preceding unsigned comment added by Dan3205 (talk • contribs) 04:19, 25 January 2020 (UTC)