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User:Joh10192/KIAA0232

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KIAA0232

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KIAA0232 is a protein which in humans is encoded by the KIAA0232 gene.

Gene

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KIAA0232 is located at 4p16.1 neighboring TBC1 domain family member 14 and an uncharacterized locus.[1]

Chromosomal neighborhood of gene KIAA0232

Homology

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KIAA0232 is conserved in most animals, as far back as some species of nematode.

Protein

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The KIAA0232 protein is 1395 amino acids in length. There are 4 transcript variants comprised of 10 exons.

Domains

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KIAA0232 is largely composed of DUF4603

Interacting Proteins

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KIAA0232 is experimentally known to interact with YWHAZ[2], DYRK1A/B[3], SLC35F[4] via two hybrid interaction experiments.

Clinical Significance

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References

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  1. ^ "KIAA0232 KIAA0232 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2016-04-28.
  2. ^ Bandyopadhyay, Sourav; Chiang, Chih-yuan; Srivastava, Jyoti; Gersten, Merril; White, Suhaila; Bell, Russell; Kurschner, Cornelia; Martin, Christopher H; Smoot, Mike. "A human MAP kinase interactome". Nature Methods. 7 (10): 801–805. doi:10.1038/nmeth.1506.
  3. ^ Varjosalo, Markku; Keskitalo, Salla; Van Drogen, Audrey; Nurkkala, Helka; Vichalkovski, Anton; Aebersold, Ruedi; Gstaiger, Matthias (2013-04-25). "The Protein Interaction Landscape of the Human CMGC Kinase Group". Cell Reports. 3 (4): 1306–1320. doi:10.1016/j.celrep.2013.03.027. ISSN 2211-1247. PMID 23602568 23602568, 23602568. {{cite journal}}: Check |pmid= value (help); no-break space character in |last3= at position 4 (help)
  4. ^ Stelzl, Ulrich; Worm, Uwe; Lalowski, Maciej; Haenig, Christian; Brembeck, Felix H.; Goehler, Heike; Stroedicke, Martin; Zenkner, Martina; Schoenherr, Anke (2005-09-23). "A Human Protein-Protein Interaction Network: A Resource for Annotating the Proteome". Cell. 122 (6): 957–968. doi:10.1016/j.cell.2005.08.029. ISSN 0092-8674. PMID 16169070 16169070, 16169070. {{cite journal}}: Check |pmid= value (help)
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