Offense
| NO | Player | POS | HT | WT | DOB (AGE) | EXP | College |
|---|---|---|---|---|---|---|---|
| 17 | B. AllenBrandon Allen | QB | 6-2 | 209 | 9/5/1992 (31) | 8 | Arkansas |
| 5 | J. DobbsJoshua Dobbs | QB | 6-3 | 220 | 1/26/1995 (29) | 8 | Tennessee |
| 4 | T. MordecaiTanner Mordecai | QB | 6-2 | 218 | 11/8/1999 (24) | R | Wisconsin |
| 13 | B. PurdyBrock Purdy | QB | 6-1 | 220 | 12/27/1999 (24) | 3 | Iowa St. |
| 49 | I. GuerendoIsaac Guerendo | RB | 6-0 | 221 | 6/28/2000 (24) | R | Louisville |
| 24 | J. MasonJordan Mason | RB | 5-11 | 223 | 5/24/1999 (25) | 3 | Georgia Tech |
| 23 | C. McCaffreyChristian McCaffrey | RB | 5-11 | 210 | 6/7/1996 (28) | 8 | Stanford |
| 25 | E. MitchellElijah Mitchell | RB | 5-10 | 200 | 5/2/1998 (26) | 4 | Louisiana |
| 38 | C. SchraderCody Schrader | RB | 5-9 | 214 | 9/8/1999 (24) | R | Missouri |
| 32 | P. TaylorPatrick Taylor | RB | 6-1 | 217 | 4/29/1998 (26) | 4 | Memphis |
| 44 | K. JuszczykKyle Juszczyk | FB | 6-2 | 235 | 4/23/1991 (33) | 12 | Harvard |
| 11 | B. AiyukBrandon Aiyuk | WR | 6-0 | 200 | 3/17/1998 (26) | 5 | Arizona St. |
| 10 | R. BellRonnie Bell | WR | 6-0 | 190 | 1/28/2000 (24) | 2 | Michigan |
| 18 | C. ConleyChris Conley | WR | 6-3 | 205 | 10/25/1992 (31) | 10 | Georgien |
| 83 | J. CowingJacob Cowing | WR | 5-9 | 170 | 2/4/2001 (23) | R | Arizona |
| 3 | F. DarbyFrank Darby | WR | 6-1 | 200 | 9/8/1997 (26) | 3 | Arizona St. |
| 6 | D. GrayDanny Gray | WR | 6-0 | 200 | 4/1/1999 (25) | 3 | SMU |
| 15 | J. JenningsJauan Jennings | WR | 6-3 | 212 | 7/10/1997 (27) | 4 | Tennessee |
| 86 | T. MartinTay Martin | WR | 6-3 | 186 | 12/14/1997 (26) | 1 | Oklahoma State |
| 84 | T. OwensTerique Owens | WR | 6-3 | 200 | 9/25/1999 (24) | R | Missouri St. |
| 14 | R. PearsallRicky Pearsall | WR | 6-1 | 189 | 9/9/2000 (23) | R | Florida |
| 1 | D. SamuelDeebo Samuel | WR | 6-0 | 215 | 1/15/1996 (28) | 6 | South Carolina |
| 19 | T. TaylorTrent Taylor | WR | 5-8 | 180 | 4/30/1994 (30) | 7 | Louisiana Tech |
| 0 | M. TurnerMalik Turner | WR | 6-2 | 202 | 1/30/1996 (28) | 5 | Illinois |
| 85 | G. KittleGeorge Kittle | TE | 6-4 | 250 | 10/9/1993 (30) | 8 | Iowa |
| 81 | C. LatuCameron Latu | TE | 6-5 | 244 | 2/24/2000 (24) | 2 | Alabama |
| 89 | M. PlineMason Pline | TE | 6-7 | 260 | 2/5/2000 (24) | R | Furman |
| 82 | E. SaubertEric Saubert | TE | 6-5 | 248 | 5/9/1994 (30) | 7 | Drake |
| 48 | L. ThomasLogan Thomas | TE | 6-6 | 250 | 7/1/1991 (33) | 10 | Virginia Tech |
| 88 | J. TongesJake Tonges | TE | 6-4 | 240 | 7/8/1999 (25) | 2 | California |
| 9 | B. WillisBrayden Willis | TE | 6-4 | 240 | 11/11/1999 (24) | 2 | Oklahoma |
| 64 | J. BrendelJake Brendel | C | 6-4 | 299 | 9/10/1992 (31) | 7 | UCLA |
| 60 | P. ElfleinPat Elflein | C | 6-3 | 305 | 7/6/1994 (30) | 8 | Ohio State |
| 66 | D. NugentDrake Nugent | C | 6-1 | 300 | 2/9/2001 (23) | R | Michigan |
| 67 | I. AlarconIsaac Alarcon | OT | 6-7 | 320 | 7/27/1998 (26) | 1 | Monterrey Institute of Tech |
| 60 | S. GutierrezSebastian Gutierrez | OT | 6-6 | 308 | 7/6/1998 (26) | 1 | Minot State |
| 61 | C. HubbardChris Hubbard | OT | 6-4 | 295 | 4/23/1991 (33) | 11 | UAB |
| 68 | C. McKivitzColton McKivitz | OT | 6-6 | 301 | 8/9/1996 (27) | 5 | West Virginia |
| 76 | J. MooreJaylon Moore | OT | 6-4 | 311 | 1/9/1998 (26) | 4 | W. Michigan |
| 75 | B. ParkerBrandon Parker | OT | 6-8 | 320 | 10/21/1995 (28) | 7 | NC A&T |
| 77 | D. PuniDominick Puni | OT | 6-5 | 313 | 2/24/2000 (24) | R | Kansas |
| 63 | N. ZakeljNick Zakelj | OT | 6-6 | 316 | 6/22/1999 (25) | 3 | Fordham |
| 78 | B. BartchBen Bartch | OG | 6-6 | 315 | 7/22/1998 (26) | 5 | St. John's (Minn.) |
| 74 | S. BurfordSpencer Burford | OG | 6-4 | 300 | 7/19/2000 (24) | 3 | Texas-San Antonio |
| 55 | J. FelicianoJon Feliciano | OG | 6-4 | 325 | 2/10/1992 (32) | 10 | Miami (Fla.) |
| 62 | J. KingstonJarrett Kingston | OG | 6-4 | 308 | 12/2/1999 (24) | R | USC |
Defense
| NO | Player | POS | HT | WT | DOB (AGE) | EXP | College |
|---|---|---|---|---|---|---|---|
| 58 | A. BarrettAlex Barrett | DE | 6-2 | 250 | 3/6/1994 (30) | 2 | San Diego St. |
| 51 | R. Beal Jr.Robert Beal Jr. | DE | 6-4 | 250 | 8/18/1999 (24) | 2 | Georgien |
| 97 | N. BosaNick Bosa | DE | 6-4 | 266 | 10/23/1997 (26) | 6 | Ohio State |
| 40 | A. BryantAustin Bryant | DE | 6-5 | 250 | 11/12/1996 (27) | 5 | Clemson |
| 56 | L. FloydLeonard Floyd | DE | 6-3 | 240 | 9/8/1992 (31) | 9 | Georgien |
| 94 | Y. Gross-MatosYetur Gross-Matos | DE | 6-5 | 265 | 2/26/1998 (26) | 5 | Penn State |
| 60 | S. BrownShakel Brown | DT | 6-3 | 295 | 12/4/1998 (25) | 2 | Troy |
| 99 | M. CollinsMaliek Collins | DT | 6-2 | 310 | 4/8/1995 (29) | 9 | Nebraska |
| 93 | K. DavisKalia Davis | DT | 6-2 | 310 | 10/2/1998 (25) | 3 | UCF |
| 92 | J. ElliottJordan Elliott | DT | 6-4 | 302 | 11/23/1997 (26) | 5 | Missouri |
| 90 | K. GivensKevin Givens | DT | 6-1 | 285 | 3/1/1997 (27) | 5 | Penn State |
| 96 | T. McGillT.Y. McGill | DT | 6-0 | 294 | 11/23/1992 (31) | 8 | NC State |
| 91 | S. OkuayinonuSam Okuayinonu | DT | 6-1 | 269 | 5/1/1998 (26) | 2 | Maryland |
| 98 | J. HargraveJavon Hargrave | NT | 6-2 | 305 | 2/7/1993 (31) | 9 | SC State |
| 66 | E. AndersonEvan Anderson | DL | 6-3 | 326 | 2/14/2002 (22) | R | FAU |
| 59 | D. CampbellDe'Vondre Campbell | OLB | 6-3 | 232 | 7/1/1993 (31) | 9 | Minnesota |
| 54 | F. WarnerFred Warner | MLB | 6-3 | 230 | 11/19/1996 (27) | 7 | BYU |
| 48 | T. BethuneTatum Bethune | LB | 6-1 | 230 | 2/19/2001 (23) | R | Florida State |
| 45 | D. Flannigan-FowlesDemetrius Flannigan-Fowles | LB | 6-2 | 223 | 9/4/1996 (27) | 5 | Arizona |
| 50 | J. GrahamJalen Graham | LB | 6-3 | 220 | 1/11/2000 (24) | 2 | Purdue |
| 36 | C. RobinsonCurtis Robinson | LB | 6-3 | 235 | 6/2/1998 (26) | 3 | Stanford |
| 47 | Z. TurnerZeke Turner | LB | 6-2 | 214 | 6/9/1996 (28) | 7 | Washington |
| 53 | D. WintersDee Winters | LB | 5-11 | 227 | 10/17/2000 (23) | 2 | TCU |
| 31 | R. GreenRenardo Green | CB | 6-0 | 186 | 11/9/2000 (23) | R | Florida State |
| 2 | D. LenoirDeommodore Lenoir | CB | 5-10 | 200 | 10/6/1999 (24) | 4 | Oregon |
| 26 | C. LucasChase Lucas | CB | 5-11 | 184 | 3/4/1997 (27) | 3 | Arizona St. |
| 28 | D. Luter Jr.Darrell Luter Jr. | CB | 6-0 | 190 | 4/24/2000 (24) | 2 | South Alabama |
| 20 | A. ThomasAmbry Thomas | CB | 6-0 | 190 | 9/9/1999 (24) | 4 | Michigan |
| 7 | C. WardCharvarius Ward | CB | 6-1 | 196 | 5/16/1996 (28) | 7 | Middle Tenn. |
| 0 | S. WomackSamuel Womack | CB | 5-10 | 189 | 7/7/1999 (25) | 3 | Toledo |
| 33 | R. Ya-SinRock Ya-Sin | CB | 5-11 | 195 | 5/23/1996 (28) | 6 | Temple |
| 22 | I. YiadomIsaac Yiadom | CB | 6-1 | 188 | 2/20/1996 (28) | 7 | Boston College |
| 30 | G. OdumGeorge Odum | DB | 6-1 | 202 | 11/3/1993 (30) | 7 | Cent. Ark. |
| 27 | J. BrownJi'Ayir Brown | SAF | 5-11 | 202 | 1/25/2000 (24) | 2 | Penn State |
| 41 | T. HawkinsTayler Hawkins | SAF | 6-1 | 205 | 12/27/1997 (26) | 1 | San Diego St. |
| 49 | J. MahoneyJaylen Mahoney | SAF | 5-11 | 200 | 11/19/2000 (23) | R | Vanderbilt |
| 43 | M. MustaphaMalik Mustapha | SAF | 5-10 | 206 | 6/25/2002 (22) | R | Wake Forest |
| 35 | E. HarrisErik Harris | FS | 6-2 | 225 | 4/2/1990 (34) | 8 | California (PA) |
Special Teams
| NO | Player | POS | HT | WT | DOB (AGE) | EXP | College |
|---|---|---|---|---|---|---|---|
| 4 | J. MoodyJake Moody | K | 6-1 | 210 | 11/23/1999 (24) | 2 | Michigan |
| 3 | M. WishnowskyMitch Wishnowsky | P | 6-2 | 220 | 3/2/1992 (32) | 6 | Utah |
| 46 | T. PepperTaybor Pepper | LS | 6-4 | 245 | 5/28/1994 (30) | 7 | Michigan St. |