Global Hepatitis Programme
The Department of Global HIV, Hepatitis and Sexually Transmitted Infections Programmes leads the development and implementation of the global health sector strategy on the elimination of viral hepatitis as a public health threat.

Strategic Information


The integrated Global Health Sector Strategies on, respectively, HIV, viral hepatitis and sexually transmitted infections for the period 2022-2030 (GHSS) re-affirm the ambitious targets set in 2016 and further define global targets for 2025 and 2030. The GHSS on viral hepatitis calls for elimination of viral hepatitis as a public health threat by 2030.

Countries should have a national health information system, which can reliably generate and analyse the data necessary to monitor and assess progress against the hepatitis elimination criteria, as well as impact and programme targets. 

Strategic information can be defined as data collected at all service delivery and administrative levels to inform policy and programme decisions. In the field of viral hepatitis, strategic information includes surveillance as well as monitoring and evaluation. Surveillance describes the epidemiological situation, from new hepatitis infections to chronic infections and sequelae that lead to morbidity and mortality.

The monitoring and evaluation framework for viral hepatitis tracks how hepatitis programmes are performing using a standard results-based approach that considers context (prevalence of infection), measures input, output and outcomes (including the cascade of prevention, testing and treatment), and impact (incidence and mortality). These components contribute to a comprehensive picture of the epidemiological situation of viral hepatitis. They provide strategic information to inform policy and programme decisions, and to monitor progress towards the elimination of viral hepatitis as a public health threat.

The data systems required to inform this framework include:

  • surveillance for acute hepatitis A–E chronic infections (mostly B and C), and sequelae (caused by decompensated liver cirrhosis and hepatocellular cancer);
  • programme data documenting prevention, testing and treatment, including the cascade of care; and
  • A stepwise approach is recommended for implementing surveillance for viral hepatitis, using the data available while strengthening the data system. In the first phase, a survey is needed to generate estimates for the epidemiology as well as the natural history of hepatitis in the country. In the second phase, person-centred routine programme data are needed to manage and monitor viral hepatitis testing and treatment coverage. 
Global hepatitis report 2024: action for access in low- and middle-income countries
This is the first consolidated WHO report on viral hepatitis epidemiology, service coverage and product access, with improved data for action. This report...
Consolidated guidelines on person-centred viral hepatitis strategic information: using data to support country scale-up of hepatitis prevention, diagnosis and treatment services
These guidelines summarize the approach proposed by WHO to collect, analyse, report, disseminate and use strategic information on viral hepatitis. They...

Strategic information measurement framework and menu of indicators for viral hepatitis monitoring

Core indicators for viral hepatitis B and C monitoring

A stepwise recommendation for strengthening country surveillance of viral hepatitis

Prevalent cases of chronic hepatitis B by WHO region, 2022 

Prevalent cases of chronic hepatitis B by WHO region, 2022

Prevalent cases of chronic hepatitis C by WHO region, 2022 

Prevalent cases of chronic hepatitis C by WHO region, 2022

Guidelines

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Publications and technical reports

Global hepatitis report 2024: action for access in low- and middle-income countries

This is the first consolidated WHO report on viral hepatitis epidemiology, service coverage and product access, with improved data for action. This report...

Guidance for country validation of viral hepatitis elimination and path to elimination

Building on the 2021 Interim guidance, this second version and update, incorporates the lessons and feedback from the hepatitis pilots that successfully...

Criteria for validation of elimination of viral hepatitis B and C: report of 7 country pilots

A series of country pilots (Brazil, Egypt, Georgia, Mongolia, Rwanda, Thailand and United Kingdom of Great Britain and Northern Ireland) of the elimination...

Global progress report on HIV, viral hepatitis and sexually transmitted infections, 2021

This report provides accountability for the 3 Global Health Sector Strategies (2016-2021) on HIV, Viral Hepatitis and the STIs. The report assesses the...

WHO implementation tool for monitoring the toxicity of new antiretroviral and antiviral medicines in HIV and viral hepatitis programmes

In the current context of treatment being rapidly scaled up, prolonged exposure to ARV drugs and transition to new antiretroviral (ARV) drugs, ARV toxicity...

Technical considerations and case definitions to improve surveillance for viral hepatitis - policy brief

In 2010 and 2014, World Health Assembly resolutions called for stronger surveillance of viral hepatitis. In response, the World Health Organization has...

Monitoring and evaluation for viral hepatitis B and C: recommended indicators and framework

To monitor and evaluate the Global Health Sector Strategy (GHSS) on viral hepatitis, the World Health Organization (WHO) proposes a monitoring and evaluation...