Global HIV Programme
The WHO Department of Global HIV, Hepatitis and Sexually Transmitted Infections Programmes leads the development and implementation of the global health sector strategy on the elimination of HIV as a public health threat.

HIV drug resistance surveillance

Global and national policy decisions on antiretroviral therapy and HIV service delivery need to be informed by reliable national data on HIV drug resistance (HIVDR) prevalence and trends. HIV treatment and pre-exposure prophylaxis scale-up should be accompanied by measures to monitor the quality of antiretroviral drug delivery and surveillance of HIVDR.

Quality data should be obtained from periodic nationally representative HIVDR surveys among different populations.

WHO HIV drug resistance database

WHO has developed an HIVDR database as a global repository of HIVDR survey data. This database includes deidentified individual-level epidemiological information linked to HIV genome sequences. The WHO HIVDR database is a platform stored on a secure United Nations server. Countries are encouraged to use the database to manage data from HIVDR surveys.

The WHO HIVDR database has 4 main functions:

  1. to support countries and genotyping laboratories in the quality assurance of epidemiological and sequence data for the purpose of generating high-quality country reports;
  2. to provide standardized HIVDR interpretations by linking to the most recent Stanford HIVDR interpretation algorithm;
  3. to support dissemination of data for global reporting; and
  4. to provide countries with a long-term secure repository for their HIVDR data.

Database access is restricted to designated ministry of health and antiretroviral therapy programme users. Designated users may request access by contacting [email protected]