BRCA1 associated RING domain 1 (Q21100416)

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mammalian protein found in Homo sapiens
  • BRCA1-associated RING domain protein 1
  • BRCA1-associated RING domain gene 1
  • RING-type E3 ubiquitin transferase BARD1
  • BARD1
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Sprache Label Description Also known as
Englisch
BRCA1 associated RING domain 1
mammalian protein found in Homo sapiens
  • BRCA1-associated RING domain protein 1
  • BRCA1-associated RING domain gene 1
  • RING-type E3 ubiquitin transferase BARD1
  • BARD1

Statements

molecular function
protein binding
determination method
IPI
18 references
retrieved
8 April 2019
stated in
BARD1 regulates BRCA1 apoptotic function by a mechanism involving nuclear retention
GOA
curator
UniProt
UniProt protein ID
Q99728
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728
determination method
IPI
retrieved
8 April 2019
stated in
Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
GOA
curator
UniProt
UniProt protein ID
Q99728
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728
determination method
IPI
retrieved
8 April 2019
stated in
Identification of a RING protein that can interact in vivo with the BRCA1 gene product
GOA
curator
UniProt
UniProt protein ID
Q99728
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728
determination method
IPI
retrieved
8 April 2019
stated in
The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function
GOA
curator
UniProt
UniProt protein ID
Q99728
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728
determination method
IPI
retrieved
8 April 2019
stated in
BARD1 induces apoptosis by catalysing phosphorylation of p53 by DNA-damage response kinase
GOA
curator
UniProt
UniProt protein ID
Q99728
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728
determination method
IPI
retrieved
8 April 2019
stated in
Mapping the functional domains of BRCA1. Interaction of the ring finger domains of BRCA1 and BARD1
GOA
curator
UniProt
UniProt protein ID
Q99728
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728
determination method
IPI
retrieved
8 April 2019
stated in
Nucleophosmin/B23 is a candidate substrate for the BRCA1-BARD1 ubiquitin ligase
GOA
curator
UniProt
UniProt protein ID
Q99728
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728
determination method
IPI
retrieved
8 April 2019
stated in
BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity
GOA
curator
UniProt
UniProt protein ID
Q99728
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728
determination method
IPI
retrieved
8 April 2019
stated in
PALB2 is an integral component of the BRCA complex required for homologous recombination repair
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728
determination method
IPI
retrieved
8 April 2019
stated in
DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728
determination method
IPI
retrieved
8 April 2019
stated in
A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728
determination method
IPI
retrieved
8 April 2019
stated in
E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728
determination method
IPI
retrieved
8 April 2019
stated in
Nuclear deadenylation/polyadenylation factors regulate 3' processing in response to DNA damage
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728
determination method
IPI
retrieved
8 April 2019
stated in
Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728
determination method
IPI
retrieved
8 April 2019
stated in
Identification of a RING protein that can interact in vivo with the BRCA1 gene product
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728
determination method
IPI
retrieved
8 April 2019
stated in
Function of BRCA1 in the DNA damage response is mediated by ADP-ribosylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728
determination method
IPI
retrieved
8 April 2019
stated in
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99728
determination method
IPI
cell component
biological process

Identifiers

 
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