Eomesodermin (Q21981066)

Transcription factor, T-box

1 reference

T-box superfamily

1 reference

T-box transcription factor-associated domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Transcription factor, T-box, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

9 May 2019

Examination of transcriptional networks reveals an important role for TCFAP2C, SMARCA4, and EOMES in trophoblast stem cell maintenance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

DNA-binding transcription factor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

1 reference

9 May 2019

The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

DNA-binding transcription repressor activity, RNA polymerase II-specific

1 reference

9 May 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

molecular function regulator

IC

1 reference

9 May 2019

Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

intracellular anatomical structure

TAS

cell component

1 reference

10 September 2018

The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface

http://www.ebi.ac.uk/QuickGO/annotations?protein=O54839&geneProductId=UniProtKB:O54839

7 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

9 May 2019

Eomesodermin is expressed in mouse oocytes and pre-implantation embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

9 May 2019

The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

9 May 2019

Scratch regulates neuronal migration onset via an epithelial-mesenchymal transition-like mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

9 May 2019

Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

9 May 2019

Proliferative defects and formation of a double cortex in mice lacking Mltt4 and Cdh2 in the dorsal telencephalon

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

regulation of neuron differentiation

biological process

1 reference

14 February 2019

The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

4 references

9 May 2019

Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

9 May 2019

Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

9 May 2019

Eomesodermin is required for mouse trophoblast development and mesoderm formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

regulation of transcription, DNA-templated

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

adaptive immune response

1 reference

9 May 2019

cerebral cortex regionalization

1 reference

9 May 2019

The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

endodermal cell fate specification

1 reference

9 May 2019

Pluripotency factors regulate definitive endoderm specification through eomesodermin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

immune system process

1 reference

9 May 2019

regulation of transcription by RNA polymerase II

1 reference

9 May 2019

Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

cardioblast differentiation

1 reference

9 May 2019

The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

negative regulation of transcription by RNA polymerase II

1 reference

9 May 2019

Brachyury and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

transcription, DNA-templated

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O54839&geneProductId=UniProtKB:O54839

mesodermal to mesenchymal transition involved in gastrulation

1 reference

9 May 2019

Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

stem cell population maintenance

1 reference

9 May 2019

Examination of transcriptional networks reveals an important role for TCFAP2C, SMARCA4, and EOMES in trophoblast stem cell maintenance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

multicellular organism development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

positive regulation of transcription, DNA-templated

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

CD8-positive, alpha-beta T cell differentiation involved in immune response

3 references

regulation of gene expression

1 reference

9 May 2019

Pluripotency factors regulate definitive endoderm specification through eomesodermin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

skeletal muscle cell differentiation

1 reference

9 May 2019

Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

cerebral cortex neuron differentiation

1 reference

9 May 2019

Tbr2 directs conversion of radial glia into basal precursors and guides neuronal amplification by indirect neurogenesis in the developing neocortex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

olfactory bulb development

1 reference

9 May 2019

Atherosclerosis in LDLR-knockout mice is inhibited, but not reversed, by the PPARgamma ligand pioglitazone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

3 references

9 May 2019

Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

9 May 2019

Pluripotency factors regulate definitive endoderm specification through eomesodermin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

9 May 2019

The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

cell differentiation involved in embryonic placenta development

1 reference

9 May 2019

Eomesodermin is required for mouse trophoblast development and mesoderm formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

regulation of neurogenesis

1 reference

14 February 2019

The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst

blastocyst development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

negative regulation of DNA-binding transcription factor activity

1 reference

9 May 2019

Brachyury and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

1 reference

9 May 2019

The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone

neuron differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

1 reference

9 May 2019

Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

anatomical structure morphogenesis

1 reference

9 May 2019

Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development

mesendoderm development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54839

Transcription factor, T-box, conserved site

has part(s)

1 reference

T-box transcription factor-associated

1 reference