AKAP9 regulation of microtubule dynamics promotes Epac1-induced endothelial barrier properties (Q34144167)

31 July 2017

title

AKAP9 regulation of microtubule dynamics promotes Epac1-induced endothelial barrier properties (English)

1 reference

31 July 2017

0 references

Seema Sehrawat

1

1 reference

31 July 2017

Thomas Ernandez

2

1 reference

31 July 2017

Xavier Cullere

3

1 reference

31 July 2017

Mikiko Takahashi

4

1 reference

31 July 2017

Yoshitaka Ono

5

1 reference

31 July 2017

Yulia Komarova

6

1 reference

31 July 2017

Tanya N. Mayadas

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20952690

4 August 2024

language of work or name

Englisch

0 references

publication date

15 October 2010

1 reference

full work available at URL

31 July 2017

https://ashpublications.org/blood/article-pdf/117/2/708/1339599/zh800211000708.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20952690

http://www.bloodjournal.org/cgi/content/abstract/117/2/708

4 August 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20952690

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20952690/?tool=EBI

4 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20952690

https://europepmc.org/articles/PMC3031489

4 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20952690

https://doi.org/10.1182/blood-2010-02-268870

4 August 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20952690

http://ashpublications.org/blood/article-pdf/117/2/708/1339599/zh800211000708.pdf

4 August 2024

file format

Portable Document Format

1 reference

10.1182/BLOOD-2010-02-268870

Crossref

DOI

https://api.crossref.org/works/10.1182/BLOOD-2010-02-268870

4 August 2024

1 reference

31 July 2017

volume

117

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31 July 2017

issue

2

1 reference

31 July 2017

page(s)

708-718

1 reference

Epac: defining a new mechanism for cAMP action

31 July 2017

cites work

1 reference

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5 July 2018

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Microtubule nucleation at the cis-side of the Golgi apparatus requires AKAP450 and GM130

5 July 2018

1 reference

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Paxillin is involved in the differential regulation of endothelial barrier by HGF and VEGF.

5 July 2018

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Neuronal AKAP150 coordinates PKA and Epac-mediated PKB/Akt phosphorylation.

5 July 2018

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A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulation

5 July 2018

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Tracking the ends: a dynamic protein network controls the fate of microtubule tips

5 July 2018

1 reference

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Role of Epac1, an exchange factor for Rap GTPases, in endothelial microtubule dynamics and barrier function

5 July 2018

1 reference

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VE-cadherin: the major endothelial adhesion molecule controlling cellular junctions and blood vessel formation

5 July 2018

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Mutation of an A-kinase-anchoring protein causes long-QT syndrome

5 July 2018

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KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell cell junctions

5 July 2018

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Krit 1 interactions with microtubules and membranes are regulated by Rap1 and integrin cytoplasmic domain associated protein-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Microtubules tethered at epithelial cell junctions by dynein facilitate efficient junction assembly

5 July 2018

1 reference

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Recruitment of CG-NAP to the Golgi apparatus through interaction with dynein-dynactin complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Epac proteins: multi-purpose cAMP targets

5 July 2018

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Integrin alphavbeta5 regulates lung vascular permeability and pulmonary endothelial barrier function

5 July 2018

1 reference

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Interplay between exchange protein directly activated by cAMP (Epac) and microtubule cytoskeleton

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Crosstalk between different adhesion molecules

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Signaling mechanisms regulating endothelial permeability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

MAGI-1 is required for Rap1 activation upon cell-cell contact and for enhancement of vascular endothelial cadherin-mediated cell adhesion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Microtubule-associated proteins (MAPs) regulate cAMP signalling through exchange protein directly activated by cAMP (EPAC).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth

5 July 2018

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Phosphorylation of the A-kinase-anchoring protein Yotiao contributes to protein kinase A regulation of a heart potassium channel

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Linking Rap to cell adhesion

5 July 2018

1 reference

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AKAP signalling complexes: focal points in space and time

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Exchange protein directly activated by cAMP (EPAC) interacts with the light chain (LC) 2 of MAP1A

5 July 2018

1 reference

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Cortical control of microtubule stability and polarization

5 July 2018

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Localized effects of cAMP mediated by distinct routes of protein kinase A.

5 July 2018

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Post-translational modifications regulate microtubule function

5 July 2018

1 reference

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CLIC4 is enriched at cell‐cell junctions and colocalizes with AKAP350 at the centrosome and midbody of cultured mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor

5 July 2018

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Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex

5 July 2018

1 reference

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Life cycle of MTs: persistent growth in the cell interior, asymmetric transition frequencies and effects of the cell boundary

5 July 2018

1 reference

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Cell cycle-dependent subcellular localization of exchange factor directly activated by cAMP.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Differential signaling of cyclic AMP: opposing effects of exchange protein directly activated by cyclic AMP and cAMP-dependent protein kinase on protein kinase B activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Integrin binding to fibronectin and vitronectin maintains the barrier function of isolated porcine coronary venules

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Phosphodiesterase 4D and protein kinase a type II constitute a signaling unit in the centrosomal area

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Characterization of a novel giant scaffolding protein, CG-NAP, that anchors multiple signaling enzymes to centrosome and the golgi apparatus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

EB1, a protein which interacts with the APC tumour suppressor, is associated with the microtubule cytoskeleton throughout the cell cycle

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Interaction of p59fyn kinase with the dynein light chain, Tctex-1, and colocalization during cytokinesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

The alpha v beta 1 integrin functions as a fibronectin receptor but does not support fibronectin matrix assembly and cell migration on fibronectin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

The molecular organization of endothelial cell to cell junctions: differential association of plakoglobin, beta-catenin, and alpha-catenin with vascular endothelial cadherin (VE-cadherin)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

The role of integrins in the maintenance of endothelial monolayer integrity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

cAMP induced Rac 1-mediated cytoskeletal reorganization in microvascular endothelium

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Cyclic nucleotide analogs as probes of signaling pathways.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

AKAP350 modulates microtubule dynamics

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Alpha(v)beta3 and alpha(v)beta5 integrins bind both the proximal RGD site and non-RGD motifs within noncollagenous (NC1) domain of the alpha3 chain of type IV collagen: implication for the mechanism of endothelia cell adhesion

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Visualization of microtubule growth in cultured neurons via the use of EB3-GFP (end-binding protein 3-green fluorescent protein).

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Dynein binds to beta-catenin and may tether microtubules at adherens junctions.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

Distinct populations of microtubules: tyrosinated and nontyrosinated alpha tubulin are distributed differently in vivo

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031489

10.1182/BLOOD-2010-02-268870

28 October 2018

Identifiers

DOI

1 reference

31 July 2017

1 reference

31 July 2017

1 reference