WHOLE GENOME SEQUENCING
Cucumbers across 14 US states recalled due to possible contamination
Whole, fresh cucumbers have been recalled by a Florida-based producer as they may be contaminated with salmonella, a gram-negative bacteria, that can cause severe diseases.
Multi-institutional team tracks virus behind India's lumpy skin cattle
IISc team led by Utpal Tatu researched LSDV strains in India, revealing high genetic variations impacting vaccine development. The study highlights the One Health approach with multidisciplinary teams to combat disease outbreaks effectively.
22 cases of Covid's JN.1 variant detected in country till Thursday
Those infected had mild upper respiratory tract infection with symptoms of mild dry cough, sore throat with or without fever, they said. In November, 62 samples were sent to different INSACOG labs for whole genome sequencing for detection of the JN.1 variant, while in December, so far, 253 samples have been sent, the sources said on Friday.
"No need to worry": Kerala Health Minister on Covid subvariant JN.1
A case of the JN.1 subvariant of COVID-19 has been identified in Kerala, India. State Health Minister Veena George reassured the public that there is no need to worry and emphasized the state's strong health system. The Union Ministry of Health has initiated preparedness measures, including a mock drill in health facilities, to evaluate public health and hospital readiness.
Marine scientists unearth genome secrets of Indian oil sardine
The CMFRI statement said the researchers have also identified the genes involved in the biosynthesis of polyunsaturated fatty acids (PUFA) of the oil sardine, offering insights into the genomic mechanisms behind the high nutritional quality of these sardines.
INSACOG to hold meeting today on genome sequencing and presence of different Covid-19 variants in India
In November INSACOG issued a bulletin mentioning that XBB BJ.1/ BM.1.1.1 detected in multiple states in India, "XBB, a BJ 1/ BM.1.1.1 recombinant lineage with a breakpoint in the spike protein is presently appearing in multiple countries. This recombinant lineage was first detected in Singapore and US and has also been identified in multiple states in India. A sub-lineage of XBB with an additional mutation is also detected (XBB.1)."
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CM Arvind Kejriwal directs health dept to ramp up genome sequencing: Officials on Covid response
"The Delhi government is keeping a watch on the Covid situation. CM Arvind Kejriwal himself is monitoring the preparedness," a senior Delhi government official said on Wednesday.
India steps up Covid genome sequencing as China cases soar
In a letter seen by AFP, the ministry said that it is "essential to gear up the whole genome sequencing of positive case samples" in order to track any new variants.
Govt directs all states to conduct genome sequencing of positive Covid cases to check for new variant
In a letter written to additional chief secretaries Principal secretaries and state health state secretaries, Union health secretary Rajesh Bhushan said that it was "essential" to gear up the whole genome sequencing of positive case samples to track the variants through lndian SARS-CoV-2 Genomics Consortium (INSACoG) network.
Team of scientists from ICAR completes genome sequencing for pomegranate
The team involved in this landmark research comprised Dr. N.V. Singh, Dr. P. Roopa Sowjanya, Dr. Shilpa Parashuram, Dr. P.G. Patil and Dr. R.A. Marathe, all at ICAR-NRCP, Solapur. It has taken the team six years in accomplishing full genomic sequencing of this Indian pomegranate.
Do you share DNA or genome with your doppelganger? Study finds new details
The doppelgängers' appearances are more attributable to shared genes than shared life experiences.
Focus on surveillance, WGS for possible mutation: Mandaviya to officials amid surge in Covid cases
Mandaviya, who chaired a meeting with key experts and officials amid an upsurge of COVID-19 cases in some states, stressed the need to focus on districts reporting high case positivity and undertake adequate testing (with higher proportion of RT-PCR) and effective surveillance to assess and control the spread of the infection in a timely manner, the Union Health ministry said in a statement.
Surge in Covid cases: States, UTs asked to submit 'larger number' of samples for whole genome sequencing
Thirty-two districts in India including 11 from Kerala and five from Maharashtra are reporting a weekly Covid positivity rate of more than 10 per cent while in 35 districts including 9 from Delhi, the weekly positivity is between 5 and 10 per cent, sources said.
View: With the advent of AI in healthcare, moving from data to actionable insights will become easier
Various studies have proved that integration of multiomics data can help identify multiple pathways and processes that drive a disease. On the basis of this, we can stratify patients for informed and targeted therapeutic disease management.
BA.2 version of Omicron identified in 18.4% samples in Tamil Nadu
It is to be noted that the BA.2 sub-variant is driving the Covid-19 cases in the UK. The genomic analysis on the samples also found that the sub-variant BA.1.1 was identified in 43 per cent of the samples while the BA.1 sub-variant was found in 37.3 per cent of the samples.
Omicron now accounts for over 90% of cases in Indian metros
Data shows that Omicron has been spreading. According to the genomic surveillance data by Insacog network, in the fourth week of December, Omicron was found in 50% of the sequenced samples. In the second and third week of January, it has crossed over 90-95% in all isolated samples.
Equipped to handle higher number of samples for genome sequencing, say labs amid Omicron scare
According to experts, Omicron is far more transmissible than the Delta variant. Cases of the latest variant of coronavirus are likely to mount in the coming days, they said given the pattern of rise in cases in a few of the major cities in South Africa.
Insacog set to add more labs for genome sequencing
Meanwhile, the Centre has notified Noida-based National Institute of Biologicals (NIB) as another laboratory to approve Covid-19 vaccine.
All 191 Covid samples genome sequenced at ILBS between Oct, Nov were Delta variant: Official
The facility at ILBS is equipped with the latest machines called NextSeq and MiSeq which can sequence the whole virus to the tune of 400 sequences per week. The Delhi government has approved a new machine for ILBS, the NovaSeq, which will allow viral sequences up to 3,000 every week.
The missing 'S' in Omicron can help India avoid disaster
Health experts want laboratories to conduct RT-PCR tests in whole for all the three genes amid the emergence of the Omicron variant, especially for international travellers. Unfortunately, not all laboratories conducting RT-PCR tests are checking for the ‘S’ gene, Joshi said.
Govt says intensifying effort to sequence travelers from high risk countries to Omicron
The government has been keeping a track of the evolving situation with the emergence of the new Omicron variant of COVID-19 (B.1.1529) which has been classified as "Variant of Concern" by WHO on November 26. The variant was first detected in Southern Africa, has reportedly got over 30 mutations in the spike protein region, giving it the potential to develop an immune escape, and may possibly reduce the efficacy of vaccines against it, which needs further evaluation.
Genetic tests gaining popularity in India: Who will check the gene checkers?
The use of genetic tests and genomic medicine is gradually rising in India, underlining the need for a regulatory framework.
Over 16,000 COVID-19 samples sent for whole genome sequencing in July, August: Centre
Genomic surveillance of SARS-COV-2 is crucial to determine incidence and prevalence of the variants of concern. "It is clarified that the number of sequences, as quoted in the report, seems to be taken from Indian COVID19 Genome Surveillance portal," the ministry said.
Coronavirus: Scientists from 4 BRICS nations to carry out genomic sequencing, mathematical modelling
A whole-genome sequencing is required for the identification of genetic mutations and recombinations of the virus, while epidemiological studies can help assess its distribution. Mathematical modelling is required to project its future spread.
Genome of salt-secreting mangrove species decoded by DBT
The genomic resources generated will pave the way for researchers to study the potential of the identified genes for developing drought and salinity tolerant varieties of important crop species of the coastal region that is significant for India with 7,500 kilometres of coastline and two major island systems, it added.
Two +ve tests at interval of 102 days with one -ve defined as SARS-CoV-2 re-infection: ICMR study
According to the study 'SARS-CoV-2 re-infection: development of an epidemiological definition from India' which has been published by Cambridge in the Epidemiology and Infection journal, an investigation was conducted with the objective to develop an epidemiological case definition of possible SARS CoV-2 re-infection and assess its magnitude in India.
New findings may shed light on why the UK variant of COVID-19 is more infectious
The B.1.1.7 variant of SARS-CoV-2 was discovered in Kent, UK in December 2020, and has since spread across the globe, contributing to the increase in cases being seen in Europe and Britain's own second wave of the pandemic earlier in the year, Shefield University said in a press release on Friday.
Genome sequencing of coronavirus in sewage can help detect local variants: Study
According to the research, published in the peer-reviewed journal mBio, the ability to track SARS-CoV-2 mutations in wastewater could be particularly useful for tracking new variants like the B.1.17 strain which is now widespread in the UK and has already been introduced in several countries, including India.
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