Prevention of Dental Caries and Erosive Tooth Wear

A special issue of Dentistry Journal (ISSN 2304-6767). This special issue belongs to the section "Preventive Dentistry".

Deadline for manuscript submissions: closed (27 August 2024) | Viewed by 5022

Special Issue Editors


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Guest Editor
Department of Pediatric Dentistry, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA, USA
Interests: cariology; microbiology; pediatric dentistry; infant oral health; early childhood caries

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Guest Editor
Division of Diagnostic Sciences, Adams School of Dentistry, University of North Carolina, Chapel Hill, NC, USA
Interests: cariology; microbiology; pediatric dentistry

Special Issue Information

Dear Colleagues,

Dental enamel is the hardest substance in the human body. It acts as a barrier to protect the teeth from physical, thermal, and chemical forces. Dental erosion is a chemical condition characterized by the loss of mineralized tooth substance caused by acids of intrinsic or extrinsic origin, not derived from oral bacteria, while dental caries is a disease characterized by the demineralization of tooth tissues due to acids produced by oral bacteria in the biofilm in the presence of fermentable carbohydrates.

This Special Issue aims to discuss the symptoms and clinical presentation of dental erosion and caries and provide guidance on important strategies that can be used to prevent acid challenges and the loss or repair of tooth enamel.

Therefore, studies focusing on the prevention and control of erosion and caries are of particular interest. We are inviting relevant original research, systematic reviews, meta-analyses, and short communications covering these topics.

Dr. Adriana Modesto
Dr. Apoena Ribeiro
Guest Editors

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Keywords

  • dental enamel
  • dental caries
  • dental caries prevention
  • dental caries control
  • tooth wear

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Published Papers (3 papers)

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Research

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10 pages, 1242 KiB  
Article
Effectiveness of New Isomalt-Containing Toothpaste Formulations in Preventing Dental Caries: A Microbial Study
by Bennett Tochukwu Amaechi, Parveez Ahamed Abdul Azees, Sahar Mohseni, Maria Camila Restrepo-Ceron, Yuko Kataoka, Temitope Olabisi Omosebi and Kannan Kanthaiah
Dent. J. 2024, 12(9), 290; https://doi.org/10.3390/dj12090290 - 12 Sep 2024
Viewed by 545
Abstract
This study investigated the efficacy of Isomalt-containing toothpaste in preventing development of dental caries. Methods: Human dental enamel slabs were allocated to six groups (30/group) at random: De-ionized distilled water (DDW), and toothpaste containing 10% Isomalt, 1100 ppm fluoride, 0.05% cetylpyridinium chloride [CPC] [...] Read more.
This study investigated the efficacy of Isomalt-containing toothpaste in preventing development of dental caries. Methods: Human dental enamel slabs were allocated to six groups (30/group) at random: De-ionized distilled water (DDW), and toothpaste containing 10% Isomalt, 1100 ppm fluoride, 0.05% cetylpyridinium chloride [CPC] (ICT); 10% Isomalt, 1100 ppm fluoride (IT); 10% Isomalt, 1100 ppm fluoride, 1.5% Sodium lauryl sulfate [SLS] (IST); 1100 ppm fluoride only (FT); 1100 ppm fluoride with SLS (FST). The enamel slabs were exposed to caries development via plaque growth in a Microbial Caries Model for 7 days. Toothpastes were applied as slurries (one toothpaste–three DDW) for 2 min twice daily. Demineralization was measured as the change in surface microhardness (ΔSMH) and amount of mineral lost (∆Z), and these metrics were assessed using Transverse Microradiography. Intra-group (SMH) and intergroup (%∆SMH and ∆Z) comparisons were paired t-test and Tukey’s test (α = 0.05), respectively. Results: With SMH, demineralization was found to be significant (p < 0.001) in all groups compared to sound enamel baseline, except ICT group. With %ΔSMH, all other groups had significantly (p < 0.001) less demineralization compared to DDW. Significantly (p < 0.001) greater demineralization was observed in IT, FT and FST compared to ICT, and no significant difference was observed between IST and ICT or FT. With ∆Z, relative to the DDW group, the inhibition of demineralization was significant (p < 0.0001) in all groups at varying percentages. Conclusions: Toothpaste containing 10% Isomalt, 1100 ppm fluoride, and 0.05% CPC demonstrated greater efficacy in inhibiting caries development amid dental plaque compared to toothpaste containing only 1100 ppm fluoride. Full article
(This article belongs to the Special Issue Prevention of Dental Caries and Erosive Tooth Wear)
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12 pages, 1048 KiB  
Article
Adhesive Performance of Pit and Fissure Sealants on Deproteinized Enamel with Different Proteolytic Agents: In Vitro Study
by Luis Francisco García-Mota, Miguel-Ángel Fernández-Barrera, Rene Garcia-Contreras, Guillermo Grazioli, Juan Eliezer Zamarripa-Calderón, José Alejandro Rivera-Gonzaga and Carlos Enrique Cuevas-Suárez
Dent. J. 2024, 12(7), 206; https://doi.org/10.3390/dj12070206 - 4 Jul 2024
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Abstract
The objective of this work was to assess the efficacy of different proteolytic agents on the bond strength of pit and fissure sealants to bovine enamel. Eighty-four bovine enamel specimens were randomly assigned in groups according to the pit and fissure sealant applied [...] Read more.
The objective of this work was to assess the efficacy of different proteolytic agents on the bond strength of pit and fissure sealants to bovine enamel. Eighty-four bovine enamel specimens were randomly assigned in groups according to the pit and fissure sealant applied (HelioSeal F or Dyad Flow). Then, the specimens were subdivided according to the proteolytic agent used (n = 7): Group 1, distilled water (control); Group 2, 10 wt.% Tergazyme®; Group 3, 10 wt.% ZYME®; Group 4, 10% papain gel; Group 5, 10% bromelain gel; and Group 6, 5.25 wt.% sodium hypochlorite. The cell viability of the proteolytic solutions was assessed through the MTT assay. The proteolytic agents were applied on the enamel surface prior to the acid-etching procedure; then, the pit and fissure sealants were placed. The micro-shear bond strength was evaluated after 24 h or 6 months of water storing at 37 °C. Representative SEM images were taken for each experimental group. The bond strength data were statistically analyzed by a three-way ANOVA test using a significance level of α = 0.05. Bromelain and papain proteolytic solutions did not exert any cytotoxic effect on the human dental pulp cells. After 24 h and 6 months of aging, for both pit and fissure sealants, sodium hypochlorite, papain, bromelain, and Tergazyme® achieved statistically significant higher bond strength values (p < 0.05). Irrespective of the deproteinizing agent used, Dyad Flow resulted in a better bond strength after 6 months of aging. The type 1 etching pattern was identified for sodium hypochlorite, papain, and bromelain. Tergazyme®, papain, and bromelain demonstrated efficacy in deproteinizing enamel surfaces prior to acid etching, leading to the improved bond strength of pit and fissure sealants. Clinically, this suggests that these proteolytic agents can be considered viable alternatives to traditional methods for enhancing sealant retention and longevity. Utilizing these agents in dental practice could potentially reduce sealant failures. Full article
(This article belongs to the Special Issue Prevention of Dental Caries and Erosive Tooth Wear)
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20 pages, 1610 KiB  
Systematic Review
Advances in Preventive and Therapeutic Approaches for Dental Erosion: A Systematic Review
by Francesco Inchingolo, Gianna Dipalma, Daniela Azzollini, Irma Trilli, Vincenzo Carpentiere, Denisa Hazballa, Ioana Roxana Bordea, Andrea Palermo, Alessio Danilo Inchingolo and Angelo Michele Inchingolo
Dent. J. 2023, 11(12), 274; https://doi.org/10.3390/dj11120274 - 29 Nov 2023
Cited by 5 | Viewed by 3332
Abstract
This review discusses both preventive measures and clinically implemented therapy procedures that have been developed recently for the prevention and treatment of tooth erosion. Methods: The databases PubMed, Scopus, and Web of Science were used for a thorough search. Studies on the prevention [...] Read more.
This review discusses both preventive measures and clinically implemented therapy procedures that have been developed recently for the prevention and treatment of tooth erosion. Methods: The databases PubMed, Scopus, and Web of Science were used for a thorough search. Studies on the prevention and treatment of dental erosion that were conducted in English and used in vitro were among the inclusion criteria. Results: The search turned up 391 papers in total, with 34 of those publications matching the requirements for inclusion. Varnishes, toothpastes, and solutions containing fluoride and other substances were used as preventive measures. Conclusions: Dental erosion is a significant issue, and taking preventative steps is crucial to lessening the disease’s spread and its effects. Interventions based on fluoride seem to be successful at halting erosion and encouraging remineralization. To effectively address severe tooth erosion, therapeutic methods, including composite restorations, prosthetic crowns, and veneers, are available. Dental erosion causes aesthetic and functional issues that are best addressed with less invasive treatments like direct composite restorations. To improve and broaden the range of available treatments for this common dental issue, additional research and development are required. Full article
(This article belongs to the Special Issue Prevention of Dental Caries and Erosive Tooth Wear)
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