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ADCY3

From Wikipedia, the free encyclopedia
ADCY3
Identifiers
AliasesADCY3, AC3, AC-III, adenylate cyclase 3, BMIQ19
External IDsOMIM: 600291; MGI: 99675; HomoloGene: 2978; GeneCards: ADCY3; OMA:ADCY3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001159536
NM_001159537
NM_138305

RefSeq (protein)

NP_001153008
NP_001153009
NP_612178

Location (UCSC)Chr 2: 24.82 – 24.92 MbChr 12: 4.18 – 4.26 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Adenylyl cyclase type 3 is an enzyme that in humans is encoded by the ADCY3 gene.[5][6]

Function

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This gene encodes adenylyl cyclase 3, which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP).[6]

The ADCY3 subtype likely mediates odorant detection (possibly) via modulation of intracellular cAMP concentration.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000138031Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020654Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Yang B, He B, Abdel-Halim SM, Tibell A, Brendel MD, Bretzel RG, Efendic S, Hillert J (Jan 1999). "Molecular cloning of a full-length cDNA for human type 3 adenylyl cyclase and its expression in human islets". Biochemical and Biophysical Research Communications. 254 (3): 548–551. doi:10.1006/bbrc.1998.9983. PMID 9920776.
  6. ^ a b "Entrez Gene: ADCY3 adenylate cyclase 3".
  7. ^ "Gene Cards: ADCY3 Gene". Retrieved 2012-12-30.
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Further reading

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