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ADCY9

From Wikipedia, the free encyclopedia
ADCY9
Identifiers
AliasesADCY9, AC9, ACIX, adenylate cyclase 9
External IDsOMIM: 603302; MGI: 108450; HomoloGene: 868; GeneCards: ADCY9; OMA:ADCY9 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001116

NM_001291910
NM_009624

RefSeq (protein)

NP_001107

NP_001278839
NP_033754

Location (UCSC)Chr 16: 3.95 – 4.12 MbChr 16: 4.11 – 4.24 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Adenylyl cyclase type 9 is an enzyme that in humans is encoded by the ADCY9 gene.[5][6]

Function

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Adenylyl cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000162104Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000005580Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Hacker BM, Tomlinson JE, Wayman GA, Sultana R, Chan G, Villacres E, Disteche C, Storm DR (Apr 1999). "Cloning, chromosomal mapping, and regulatory properties of the human type 9 adenylyl cyclase (ADCY9)". Genomics. 50 (1): 97–104. doi:10.1006/geno.1998.5293. PMID 9628827.
  6. ^ a b "Entrez Gene: ADCY9 adenylate cyclase 9".
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Further reading

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