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C-Myc

本页使用了标题或全文手工转换
维基百科,自由的百科全书
c-Myc
已知的結構
PDB直系同源搜索: PDBe RCSB
識別號
别名MYC;, MRTL, MYCC, bHLHe39, c-Myc, v-myc avian myelocytomatosis viral oncogene homolog, MYC proto-oncogene, bHLH transcription factor, Genes, myc, c-myc
外部IDOMIM190080 MGI97250 HomoloGene31092 GeneCardsMYC
基因位置(人类
8號染色體
染色体8號染色體[1]
8號染色體
c-Myc的基因位置
c-Myc的基因位置
基因座8q24.21起始127,735,434 bp[1]
终止127,742,951 bp[1]
直系同源
物種人類小鼠
Entrez
Ensembl
UniProt
mRNA​序列

NM_002467
​NM_001354870

NM_001177352
​NM_001177353
​NM_001177354
​NM_010849

蛋白序列

NP_002458
​NP_001341799

NP_001170823
​NP_001170824
​NP_001170825
​NP_034979

基因位置​(UCSC)Chr 8: 127.74 – 127.74 MbChr 15: 61.86 – 61.86 Mb
PubMed​查找[3][4]
維基數據
檢視/編輯人類檢視/編輯小鼠

C-MycMyc是编码转录因子调节基因。这一基因编码的蛋白在细胞核内被磷酸化,有多种功能:在细胞周期进程、细胞凋亡和细胞轉化中发挥作用。[5]

相互作用

[编辑]

Myc可与以下蛋白质发生交互作用

参考文献

[编辑]
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