TB INFECTION
IISc researchers design novel 3D hydrogel culture to study TB infection and treatment
Mycobacterium tuberculosis (Mtb) is a dangerous pathogen. In 2022, it affected 10.6 million people and caused 1.3 million deaths, according to the WHO. “It is a very old bug, and it has evolved with us quite a bit,” said Rachit Agarwal, Associate Professor at BE. Mtb primarily infects the lungs, IISc said in a press release.
TB outbreak in California's Long Beach: 1 dead, 170 likely to be exposed
Tuberculosis (TB) is a bacterial infection primarily caused by Mycobacterium tuberculosis.
New AI model predicts personalised TB treatments, study shows
A new artificial intelligence (AI) model developed by scientists has the potential to revolutionise tuberculosis (TB) treatment by predicting personalised treatment outcomes. Published in the journal iScience, the study analysed diverse biomedical data from TB patients, including clinical tests, genomics, medical imaging, and drug prescriptions.
Extent of TB's hold on India revealed by new data; here are key things to know about the disease
Nearly 25 people were diagnosed with tuberculosis every hour in Maharashtra, reports based on the data shows. As of now, Uttar Pradesh has the highest number of tuberculosis cases at 5,51,372, followed by Maharashtra at 2,10,000.
Victorian disease that killed millions makes a comeback. Know about its symptoms, treatment, revival in UK
This disease was once a scourge and it killed an estimated four million people between 1851 and 1910. Now, it can be cured with antibiotics and most people will make a full recovery. But it has returned and it remains the second-biggest killer infection worldwide after Covid. Know about the disease.
64-year-old Bengaluru resident dies due to COVID-19 infection
Asserting that there is no need for any worry, Rao said the state government has made it mandatory for all health workers to wear masks, as they will be more exposed to infections. The Minister pointing out that the new variant has been found in various countries, and its spread may be fast like in the case of Omicron infections, but is not "strong and life threatening" as in the case of COVID first and second waves.
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64-year-old Bengaluru resident dies due to COVID-19 infection
Karnataka government on Tuesday issued an advisory asking people above 60 years, those with comorbidities, pregnant women and lactating mothers, to wear face masks when outdoor, and to strictly avoid visiting closed, poorly ventilated spaces and crowded areas, in the wake of current Covid-19 situation in the country and detection of JN.1 sub variant in neighbouring Kerala.
J&J, Lupin cut prices for tuberculosis drug in lower-income countries
Johnson & Johnson and Lupin will supply their versions of the tuberculosis drug bedaquiline at a significantly cheaper price in low- and middle-income countries, according to the Stop TB Partnership. The new prices, $130 for J&J and $194 for Lupin for a six-month course of treatment, represent a 55% and 33% reduction, respectively. Bedaquiline is a key part of recommended treatment regimens for drug-resistant TB infections, and this price reduction will help broaden access to the life-saving drug.
HIV infections on the rise in the state: Assam State AIDS Control Society
ASACS added although sexual transmission has always been a main route of HIV transmission in the state, it has been observed that sharing of infected needles and syringes by the injecting drug users has also become a major cause of HIV transmission in Assam during the recent years which is a matter of concern.
$46 yield per dollar invested: Here's why the world should invest more to eradicate tuberculosis
The world is failing to address tuberculosis (TB) and meet the 2030 Sustainable Development Goals (SDGs), with current trends showing a 50-year delay in achieving all goals, according to a peer-reviewed study. The study shows that allocating an additional $5bn annually could deliver diagnosis, care and prevention and ensure at least 95% of people with TB receive a diagnosis.
India develops own model for estimating TB cases in country
India has become the first country in the world to have developed a country-level mathematical model to estimate the prevalence of TB cases. Using this model, TB incidence and mortality estimate data for India will be available by March every year.
World TB Day: Once regarded as a death sentence, tuberculosis is mostly curable today; six red flags to watch out for
Men, the elderly are more vulnerable to TB.
Clinical trials of new BCG vaccine for TB to start soon, says former CSIR chief
According to the India TB Report 2022, the number of 'incident TB patients' (new and relapse cases) notified during 2021 stood at 19.3 lakh. On the government's aim to make India TB-free by 2025, former director-general of the CSIR Dr Shekhar Mande said, "There is a very serious effort going across various agencies in the country. The department of health research, department of bio-technologies, CSIR, all of them are working towards TB-free 2025."
WHO: Tuberculosis cases rise for the first time in years
The COVID-19 pandemic disrupted services for people with TB along with many other health programs. WHO said many people went undiagnosed, noting that the number of people newly identified with TB fell from 7 million in 2019 to 5.8 million in 2020.
ICMR's top research institute developing sputum-free tests for diagnosing TB
Tuberculosis is diagnosed by detecting the bacteria in the sputum. But in blood-based biomarker discovery scientists are looking at how the TB bacteria affects the host's immune system, said Dr Subash Babu, an NIH scientist and Scientific Director of ICER-India. The ICER in collaboration with NIRT is doing the research in this matter.
Health Secretary Rajesh Bhushan on key WHO panel during 75th World Health Assembly
The World Health Assembly functions through two types committee -- Committee A and Committee B, an official said. Bhushan has been appointed the Chairperson of Committee B.
Tuberculosis impacts your eyes, brain & skin. Here’s how to detect the ailment and manage it
Common symptoms of TB include fever, convulsions, weakness, and confusion.
Go for test for TB, other conditions if cough persists for more than 2-3 weeks: Revised clinical guidance for Covid patients
The revised guidelines continue to recommend emergency use authorization (EUA) or off-label use of remdesivir in patients with "moderate to severe" disease and those with no renal or hepatic dysfunction within 10 days of the onset of any symptom.
South East Asian health ministers commit to speed up efforts to end TB
They ministers agreed to increase budgetary and human resource allocations including upfront investments required to catch-up on lost ground during the COVID-19 pandemic. It is estimated that $3 billion may be needed annually to implement comprehensive set of interventions required to end TB in the Region.
Tuberculosis, the forgotten pandemic relying on a 100-year-old vaccine
Both TB and COVID are infectious diseases that generally affect the lungs. Both are passed between people mainly by aerosols, when infected people cough, sing or otherwise release them into the surrounding air. So some of the things we're used to doing for COVID-19 - like wearing masks and good ventilation - also work for preventing the spread of TB.
Diabetics who recovered from Covid may show signs of tuberculosis
Acid-Fast Bacillus causes tuberculosis and other infections.
View: Covid set back our fight against TB, but its lessons are strengthening TB management now
In every adversity lies an opportunity, and this pandemic has provided us with one to augment TB elimination efforts by strengthening our public health system and infectious diseases control actions. Dedicated infectious disease hospitals that are being established as part of our pandemic preparedness and response, will contribute significantly to TB care and management.
World Tuberculosis Day: TB is curable. Visit a doctor if you experience chest or joint pain, evening fever
India alone accounts for one fourth of the global TB burden.
View: Covid should set the stage for India’s drive against more common and fatal diseases
The emergence of multi-drug-resistant (MDR) TB strain is especially concerning, as it is resistant to the two most effective anti-TB drugs available: isoniazid and rifampicin.
Experts looking to modify TB test to track Covid-19 infection
Experts are looking at modifying the cartridge-based nuclei acid amplification test — CBNAAT diagnostic test of GeneXpert — so that it can be used for testing the coronavirus. “A different type of cartridge will be required, and will be procured,” a senior government official said on the condition of anonymity.
World Tuberculosis Day: Disease causes infertility, only lungs are at serious danger, and other myths busted
TB is one of the most-misunderstood diseases with many misconceptions surrounding it.
Regulator waives off clinical trials, clears Sanofi TB Drug
“We have recently received final approval for rifapentine from the Indian regulatory authorities. Rifapentine is now officially registered in India,” Thibaud Lefort, Sanofi’s global health business chief, told ET on the sidelines of the 50th Union World Conference of Lung Health in Hyderabad.
India continues to record maximum number of tuberculosis (TB) cases.
As per the report 10 million people had TB in 2018. While 26,90,000 people had TB in India, out of which 19,90,000 were notified.
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