COVID VACCINE CANDIDATES
![SII, the world’s largest vaccine maker, sees demand doubling in five years](https://img.etimg.com/thumb/msid-110887904,width-100,height-75,resizemode-4/industry/healthcare/biotech/pharmaceuticals/sii-the-worlds-largest-vaccine-maker-sees-demand-doubling-in-five-years.jpg)
SII, the world’s largest vaccine maker, sees demand doubling in five years
Serum Institute of India Pvt. is gearing up to meet the growing demand for life-saving vaccines, with expectations to double sales in the next five years. The world's largest vaccine maker, based in Pune, currently has the capacity to produce 3 billion doses annually but only sells about half of that. CEO Adar Poonawalla is optimistic about the increasing uptake of vaccines globally as countries boost their healthcare budgets.
![Donald Trump booed and heckled by raucous crowd at Libertarian convention](https://img.etimg.com/thumb/msid-110449032,width-100,height-75,resizemode-4/news/international/world-news/donald-trump-booed-and-heckled-by-raucous-crowd-at-libertarian-convention.jpg)
Donald Trump booed and heckled by raucous crowd at Libertarian convention
At the Libertarian National Convention, Donald Trump faced boos and heckling from attendees displeased with his past COVID-19 policies. Despite some support, most libertarians criticized him for rushing the vaccine and not opposing health restrictions. Trump's appeal for unity against Biden received mixed reactions. He promised to commute Ross Ulbricht's life sentence if re-elected, gaining significant applause. Trump's appearance highlights his concern over third-party candidate Robert F. Kennedy Jr., who also seeks libertarian support.
![BJP going to win only one seat in UP: Rahul Gandhi](https://img.etimg.com/thumb/msid-110250279,width-100,height-75,resizemode-4/news/elections/lok-sabha/uttar-pradesh/bjp-going-to-win-only-one-seat-in-up-rahul-gandhi.jpg)
BJP going to win only one seat in UP: Rahul Gandhi
Rahul Gandhi claims BJP winning only one seat of Kyoto (Varanasi) in UP during joint meeting with Akhilesh Yadav. Modi aims to turn Varanasi into Kyoto. Fight to save Constitution against BJP and RSS attacks. Promises on MSP for farm produce and youth support. Akhilesh Yadav highlights BJP's threat to lives and Constitution, promises jobs under INDIA bloc government.
![AAP 'urban Naxal party', win for candidate backed by it will bring Maoist menace, says Amit Shah](https://img.etimg.com/thumb/msid-109841063,width-100,height-75,resizemode-4/news/elections/lok-sabha/india/aap-urban-naxal-party-win-for-candidate-backed-by-it-will-bring-maoist-menace-says-amit-shah.jpg)
AAP 'urban Naxal party', win for candidate backed by it will bring Maoist menace, says Amit Shah
Addressing a rally in support of BJP candidate Dhaval Patel in Vansda, Shah said, "The Congress and urban Naxal party AAP have come together to disturb the peace of this tribal region. Do you want extortion to start in Valsad? Will you allow Naxalism to raise its head in our forest areas?" "Naxalism and urban naxalism will begin here if their candidate wins," Shah asserted.
![Heart-related tests be made free for those who took Covid vaccine, says Akhilesh Yadav](https://img.etimg.com/thumb/msid-109823144,width-100,height-75,resizemode-4/news/elections/lok-sabha/uttar-pradesh/heart-related-tests-be-made-free-for-those-who-took-covid-vaccine-says-akhilesh-yadav.jpg)
Heart-related tests be made free for those who took Covid vaccine, says Akhilesh Yadav
Akhilesh Yadav criticizes Covid vaccine, demands free heart tests. AstraZeneca's Vaxzevria linked to blood clot side effect. Criticizes BJP leaders, emphasizes public rights, inflation reduction, democracy preservation, youth future, 2024 Lok Sabha elections.
![We're alive because Modi ensured COVID vaccine for us: Fadnavis](https://img.etimg.com/thumb/msid-109649447,width-100,height-75,resizemode-4/news/politics-and-nation/were-alive-because-modi-ensured-covid-vaccine-for-us-fadnavis.jpg)
We're alive because Modi ensured COVID vaccine for us: Fadnavis
Indian Prime Minister Narendra Modi has been credited with facilitating the manufacture and administration of the COVID vaccine during the pandemic, according to Maharashtra Deputy Chief Minister Devendra Fadnavis. Nearly 100 countries credit Modi for providing vaccine doses and protecting their citizens from the virus, referring to the Centre's 'Vaccine Maitri' initiative. Fadnavis said that the world did not know that Modi was at the helm of India's leadership who knew how to protect his people.
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Who is Robert F. Kennedy Jr. and why is he running for president?
Kennedy, 70, is a member of perhaps the nation's most famous political dynasty. His uncle was President John F. Kennedy. His father served as attorney general and a U.S. senator before seeking the Democratic nomination for president. Both were assassinated.
Joe Biden will drop out of US Presidential Election 2024, top JPMorgan strategist predicts. Here is what he has said
A senior JPMorgan Chase strategist has predicted that Joe Biden will bow out of the US President Election 2024. He has given reasons for this. He has also made other predictions. Know what he has said.
Study finds being overweight hampers body's immune response to Covid infection
However, the study indicated that an elevated BMI did not impact the antibody response to COVID-19 vaccination approximately six months after the second dose.
US Presidential Election 2024: Dates, candidates and latest issues
Leading the field of Republican presidential candidates is former President Donald Trump, who faces a battery of federal and state criminal charges related to his efforts to overturn his 2020 election loss to Democrat Joe Biden.
Novavax lays off 25% of workforce, releases 2023 outlook
Biotech firm Novavax is reducing its global workforce by 25% as it pushes ahead with cost-cutting measures aimed at dealing with sluggish demand for its COVID-19 vaccines and generating revenue. The layoffs, which are part of plans aimed at cutting research and commercial costs by up to 25%, would involve about 498 jobs out of its current 1,992 full-time employees.
Serum Institute seeks inclusion of Covovax on CoWIN as heterologous booster dose for adults
Last month, COVID-19 Working Group headed by Dr N K Arora had also recommended to the health ministry inclusion of Covovax on the CoWIN portal as a heterologous booster dose for adults who have been vaccinated with two doses of either Covishield or Covaxin.
Cancer vaccines are being developed using tech similar to that used for Covid shots
Decades before Covid vaccines, scientists had been working on messenger ribonucleic acid (mRNA) vaccines targeting cancer.
Govt panel recommends market authorisation for Covovax jab as heterologous booster dose
Prakash Kumar Singh, director (government and regulatory affairs) at Serum Institute of India (SII) had recently written a letter to Drugs Controller General of India (DCGI) for approval of Covovax heterologous booster dose for those aged 18 years and above in view of escalating COVID-19 pandemic situation in some countries, official sources said.
Serum Institute seeks drug regulator's approval for market authorisation of its Covid vaccine as booster dose
Prakash Kumar Singh, director, government and regulatory affairs, SII, submitted a market authorisation application for the heterologous booster dose of Covovax to the drugs controller general of India (DCGI) on October 17. It has been learnt that the DCGI's office had raised a few queries, after which Singh submitted a reply, mentioning about the current emerging situation caused by a new coronavirus variant.
One step closer to a universal flu vaccine?
A new study describes successful animal tests of just such a vaccine, offering hope that the country can be protected against future flu pandemics. Like the COVID vaccines made by Pfizer-BioNTech and Moderna, the experimental flu vaccine relies on mRNA.
Adar Poonawalla recounts the challenges in producing India's first COVID vaccine
Poonawalla said he even looked at diluting a stake in Serum from private equity to raise the capital but they didn't need to do it because they went to other countries and philanthropists instead who understood the urgent need of doing it.
India's 'warm' vaccine candidate effective against Delta, Omicron variants in mice: Study
The heat-tolerant COVID-19 vaccine candidate can be stored at 37 degrees Celsius for four weeks and at 100 degrees Celsius for up to 90 minutes.
Covaxin to be evaluated as COVID-19 vaccine candidate in US: Bharat Biotech
Covaxin has already been granted Emergency Use Listing (EUL) in 13 countries as on January 31 according to the WHO. Covaxin was granted EUL by the national regulator, Drugs Controller General of India (DCGI), in the age group 12 to 18 years on December 24, 2021.
Reliance Life Sciences seeks approval for Phase I trial of its Covid vaccine candidate
The Subject Expert Committee (SEC), which advises the drug regulator on applications seeking approval for vaccines, new drugs and clinical trials, will review the application at a meeting on Thursday, people in the know told ET.
Dynavax to supply its CpG 1018 adjuvant for Biological E's COVID-19 Vaccine Candidate
Pending conditional regulatory approvals in India, BE expects to commence product launch of Corbevax later this year.
Production of another COVID-19 vaccine to begin in weeks
If the trial is successful, regulators could approve the vaccine for use in the last three months of the year, the drugmakers said in a statement. Their statement quoted Thomas Triomphe, who leads vaccine research and development at Sanofi Pasteur, as saying: "We are encouraged to see first vaccinations starting to take place in such an important, pivotal Phase 3 study."
Vaccine candidate from Canada's Medicago shows strong antibody response to Covid
The vaccine produced a neutralizing response that was about 10 times higher than in people recovering from COVID-19.
Biological E gets nod for Phase III trial of its COVID-19 vaccine candidate
Its candidate includes an antigen developed by the Texas Childrens Hospital Center for Vaccine Development and in- licensed from BCM Ventures, Baylor College of Medicines integrated commercialization team, along with Dynavax Technologies Corporations advanced adjuvant CpG 1018TM.
Scale up production capacity; government will provide all possible help: PM tells vaccine manufacturers
He also assured all possible support and smooth approval process for the vaccine candidates which are currently under trial phase. The health infrastructure of our private sector has played a big role in the country's fight against COVID-19, he said.
Seven COVID-19 vaccine candidates in clinical trials, says Harsh Vardhan
Harsh Vardhan said, "Around seven more COVID vaccine candidates are in clinical trials. Some of them are in the advanced phase of the trials. Around two dozen vaccines are in pre-clinical trials."
Intranasal COVID vaccine candidate in early clinical stage of development in India: Govt
Most vaccines are administered by injection through intramuscular or subcutaneous route.
Recruiting trial volunteers for future Covid vaccines may get difficult: CEPI
Regulators around the world should be prepared for this by adapting to a pooled network of biomarkers to approve vaccines, the organisation said in a note on the future of Covid-19 vaccines.
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