Thoothukkudi Lok Sabha constituency is one of the 39 parliamentary constituencies within Tamil Nadu.
During the 2019 Parliament Election, the voter turnout for the Thoothukkudi parliamentary seat stood at 69%.
In the 2019 General Election, DMK candidate Kanimozhi Karunanidhi emerged victorious with a margin of 3,47,209 votes, garnering a total of 5,63,143 votes. Kanimozhi Karunanidhi's closest contender was Dr Tamilisai Soundararajan of the BJP, who secured 2,15,934 votes.
In 2014, J Jayasingh Thiyagaraj Natterjee of AIADMK, allied with the NDA, clinched victory in this constituency, surpassing the DMK. AIADMK amassed a total of 3,66,052 votes out of the overall 9,16,778 votes cast. DMK had previously won this seat in the 2009 Lok Sabha elections.